Given as remedies for migraine and in order to reduce fever, Antifeb. and
Exalg. have produced symptoms of collapse and cyanosis, in some instances fatal, with great
rapidity. One patient experienced from Exa/gine a sensation that his head was so large that it
seemed to occupy the whole room. Respiration was most difficult as in a bad attack of asthma,
he seized and clenched the hands of those around him. He was not an asthmatic subject. He felt
as if the diaphragm had ceased working and he must go on breathing on his own account at any
cost. Several cases of thrombosis of the lower extremities from heart weakness have followed its
use.