Brucea Antidysenterica

Lepelletier has recorded the following effects of 0.02 to 0.90 of a gramme of

Brucinum. Sudden jerking, especially of lower extremities, spreading generally but not

accompanied by trismus and tetanus, and not extending to Esophagus and pharynx as with

Strychnia. Twitching in the paralysed as well as healthy muscles. A fever of short duration ends

the attacks; after which deep sleep comes on.

Dejection, with want of sleep.—Taciturnity and hypochondriasis.—Gloomy,

melancholy humour, with indolence and lassitude.—Sad and gloomy humour on waking in the

morning.

2, 3. Head and Eyes.—Heaviness and confusion in the head, with sleepiness, disappearing in the

evening.—Vertigo, which occasions falling, in the evening.—Digging crawling in the top of the

head.—Headache in the evening, after having walked long in the sunshine.—Cephalalgia behind

the eyebrows, which seem to be swollen.—Shootings in the head, aggravated by walking, esp. in

the sun.—Headache aggravated by sitting, as well as after eating.—Eyes dull and swollen —Eyes

red in the corners in the evening.—Itching in the eyelids.—Eyes red and burning in the

morning.—Painful sensation in the eyes, as from sand, rendering it necessary to rub them.

6, 8. Face and Mouth.—Mealy, itching tetters on the face, followed by peeling off of the

skin.—Paleness in the face.—Slight convulsive, rapid movements in the lips——Acute pains in the

teeth and in the gums, esp. on drinking cold water——Accumulation of saliva in the mouth, forcing

one to spit continually.—Dryness and burning pain in the gullet, as if from rancid fat.

Painful sensation of fatigue in the extremities —Pinching in several parts of

the limbs.—In the evening, stiffness in the joints, and acute drawing pains in the limbs, with

shootings in the head, in the ears, and in the chest.—Dejection.—Disposition to stretch the limbs

and to yawn.—Great weariness when walking.—In the evening, nervous excitement, trembling

and tottering when walking.—Irritability, augmented in the evening.

Weak appetite; food at dinner and breakfast appears insipid.—Clammy

taste.—Empty risings.—Sensation in the stomach, as if nothing had been eaten for a long

time.—Sensation of burning and of heat in the pit of the stomach.—Sensation of throbbing in the

pit of the stomach, and in the entire abdomen.—Pressure in the stomach, immediately after eating

or drinking.—After a meal, violent beating of the heart, aggravation of headache, fermentation in

the intestines, and inclination to evacuate.—In the evening, attack of nausea, with cramp-like

pains in the abdomen, vomiting of food, and loose evacuations, with great prostration.

Painful pinching in the abdomen.—Squeezing, as from claws, in the abdomen,

followed by frequent, small, slimy evacuations—Borborygmi in the abdomen.—The pains in the

abdomen cease after the first evacuation.—Evacuations too soft, in too small quantity, and of too

light a colour.—Shootings in the umbilicus after the evacuations.—Loose evacuations, followed

by fainting which enforces lying down.—Strong disposition to loose evacuations, with colic and

flatulency.—Loose evacuations in the morning and in the evening.—Itching in the anus in the

evening.

On breathing, sensation of great weight on the whole chest.—Oppression of the

chest, with chilly disposition and great sensibility in the open air.—In the morning, on waking,

pain as from a bruise on the outside of the chest, with tensive pains on breathing deeply.—Pains,

like excoriation, in the interior of the chest, esp. in bed at night, which are most violent when

lying on the side.

Sleepiness during the entire day, esp. when seated, in the morning, after dinner, and

in the highest degree in the afternoon.—Sleepiness early in the evening.—Sleep full of dreams,

with ebullition of the blood.—Sleep troubled, with confused or frightful, terrifying

dreams.—Sleepiness alternately with want of appetite.

Chilly disposition and aversion to the open air.—Shivering and excessive

coldness.—Sweat on walking, notwithstanding the shiverings, which appear chiefly during rest.

Brucinum.

Brucine. An alkaloid obtained from the bark and seeds of Strychnos nux vomica. C23 H26

N204.

• ▸The following also have drowsiness with headache: Gins.
• ▸, Herac.
• ▸, Gels.
• ▸(difficult to

• ▸keep the eyes open), Nux m.
• ▸, Nat.
• ▸s.
• ▸, Sul.

Pains, as of fatigue, in the thighs and in the loins.—Cramp-like pain in the back of

the hand.—Miliary eruption, red, raised, and itching, on the back of the hand and on the body.—In

the evening, sensation of paralysis in the thigh—Weariness in the knees.—Curvature of the joint

of the foot, so that one walks almost on the ankle-bone.—Sensation of burning in corns.