Duboisinum

Duboisia belongs to the same order as Belladonna, and its alkaloid, Sulphate

of duboisia, has been used as a substitute for Atropine. Its application to the eye has caused

marked constitutional symptoms of fever, delirium, stupor, and dry mouth. A symptom which

• ▸may prove a keynote is "a red spot floating in the field of vision.
• ▸" Guided by this, C.
• ▸H.
• ▸Helfrich

• ▸cured a case of hyperémia of optic nerve with Duboisin 3 (NV.
• ▸A.
• ▸J.
• ▸H.
• ▸, xiii.
• ▸267).
• ▸Dryness of

mucous membranes is very characteristic. Cool feeling in the eyes. Sensation as if stepping on

empty space. Feeling of largeness in eyes, in tongue. Inability to stand with the eyes shut gives it

a place in locomotor ataxy. It has also been proved.

Excitable; tries to get off the sofa.—Stupor; though if questioned replies, but with

difficulty.—Picks at surrounding objects; slight drawings up of arms; very rest less —Carphology;

glances suspiciously under bed-clothes and behind back; left to himself upsets room in a few

moments—towels, brushes, shoes placed on bed, and boots on dressing-table; throughout air of

fun and humour; on recovery remembers nothing of what he had done.—Busy delirium; plucks at

collar of night-dress; gazes intently at foot of bedstead where no one is, reaches out toward

imaginary person or object.—Unable to concentrate thoughts on any subject; absent-minded

thoughts wander from subject to subject; forgets what he started with thoughts silly,

nonsensical.—Unable to express herself.

Heaviness of limbs, esp. lower.—General weakness, disinclination to

move.—Sense of lightness throughout body and head.—Unsteady gait, occasionally a feeling as if

he had stepped on empty space, and would catch himself for fear of falling.—Staggered, had to

concentrate his energy and look directly ahead, for on looking to one side there was disposition

of falling to the other—General trembling; unable to hold up head; hallucinations and nausea.

Dizziness; strange feeling in head, with nausea and darkly flushed face; the "strange"

feeling lasted longer than the faintness and drowsiness ensued.—Headache.—Head feels light;

vertigo on rising up or walking; great inclination to fall backward, esp. on going up stairs; almost

impossible to stand with eyes shut.—Head heavy, dizzy.—Dull pain through upper part of

eyeballs and forehead like sick-headache.

Pupils widely dilated.—Eyes feel cool——Sharp pain in upper eyeball.—Eyes feel

tired —Things seemed elevated; every time he looked up from his book a dull pain flies through

upper part of eyeballs and forehead like sick-headache; eyes felt large and protruding.—Faces

repeated in all directions.—Countenances of bystanders appear to have hollow cheeks; walls to

have great hollows excavated in them.—Hallucinations of vision: suddenly sits on ground

imagining a chair ready for him; drops a glass in mid-air instead of placing it on the table; grasps

in the air above his head for his watch which had been taken from him.—Imagined it was quite

dark when it was a bright summer afternoon.—Cannot make out print within two feet, and it

shows several colours-blue, orange, and reddish-brown, as does the ink when writing; pupils

nearly normal; a + 20 glass makes reading at normal distance possible, but eyes feel strained in

using it.—Appearance of a red spot in field of vision moving with the eye—Hyper¢mia of optic

nerve; optic disc very red, small vessels visible, large vessels much enlarged and tortuous;

accommodation paralysed; outline of disc indistinct; arteries diminished.—Fluttering sensation in

eyeball.—Twitching of orbicularis palpebrarum.—Eyes for the most part kept closed, but opened

occasionally (in a prover).

Tongue appears to swell; becomes too large for mouth, impeding speech.—Tongue

feels "flat"; cannot articulate distinctly—Excessive dryness in mouth and throat, can scarcely

speak for it.

Throat dry; red; capillaries varicose; no secretion of any kind visible; in

consequence of the dryness the follicles are very prominent, and the conformation of spinal

column plainly visible; an almost perfect picture of "pharyngea sicca"; epiglottis hyper¢mic;

laryngeal cavity engorged, dry, with here and there patches of mucus, viscid, semi-transparent.

Next day larynx entirely dry, pharynx having isolated patches of adherent, yellowish-white

• ▸mucus.
• ▸—Constant desire to clear throat.
• ▸—Great difficulty in swallowing, esp.
• ▸empty swallowing.

Loss of appetite, nausea—Deadly "gone" feeling, as if at greater curvature, not >

by eating or drinking; pulse feeble and intermittent.

Constant desire to pass water, with great difficulty in doing so.—No urine

passed; bowels inactive; bathed in sweat.—Slight burning in urethra during micturition.

Hoarseness.—Hard, dry, hacking cough caused by tickling at about

bifurcation of trachea; cough = feeling of soreness or rawness over whole of both lungs, esp.

• ▸lower lobe |.
• ▸and upper r.
• ▸; cough not > or < by anything.
• ▸—Respiration puffy and noisy.

A rapid pulse.—Faintness.—Sense of oppression and longing to get rid of the

medicine (immediately after the dose in a poisoning case); increased to agony.—Agony of

breathlessness and sense of impending death.—Pulse rate falls on sitting up and increases on

lying down.—Pulse irregular and intermittent.

• ▸20, 21.
• ▸Back and Limbs.
• ▸—L.
• ▸leg powerless, r.
• ▸leg rigid—Arms frequently and involuntary

jerked away from the sides.—Dorsal and lumbar muscles thrown into violent rhythmic

contractions.—Loss of power in lower limbs; staggers as if drunk. —Going down stairs or kerb-

stones is difficult, every step jolting his back "as if he had stepped down from the top of a

house.".—Severe pressive pain in lumbar region in each side on waking, > on moving

about.—Peculiar sensation in legs, then in thighs, arms, and other parts of the body, as if they

were asleep.

Stupor which is not sleep, he replies if questioned.—Sleepy.—Drowsiness and

rambling.

Complained of chilliness—Temperature 100.5°—Cold and chilly, wants to wear

extra clothing, which makes him feel comfortable-—Bathed in sweat.

• ▸Delirium.
• ▸Drowsiness.
• ▸Eyes: dilated pupils.
• ▸Locomotor ataxy.
• ▸Mouth, dryness of.

• ▸Paralysis.
• ▸Presbyopia.
• ▸Throat, dryness of.
• ▸Vertigo.
• ▸Vision, disorders of.

• ▸Antidoted by: Coffee; lemon-juice.
• ▸Compare: Bell.
• ▸, Atrop.
• ▸, Dulc.
• ▸, Stram.
• ▸, &c.

Anhalonium (coloured vision).