"Nitro-glycerine was discovered by Sobrero in 1847, but none could be
obtained for physiological experiment until Morris Davis, a Philadelphia chemist, in the same
year, after long and laborious trials, under direction of Hering, succeeded in producing the
- substance in sufficient quantities for proving.
- " I quote this from the Guiding Symptoms.
- Glon.
- is
one of the many monuments of Hering's therapeutic genius. It is to him that we owe the
introduction of this notable remedy into the materia medica, and into medicine. The note of the
action of G/on. is a tendency to sudden and violent irregularities of the circulation. It acts very
quickly and very violently. The "signature" of this potent explosive may be said to be "bursting"
and "expansion." Bursting, throbbing headaches; sensations of expanding in the head and
elsewhere. Throbbing of carotids; violent action of heart; rush of blood to head; flushes of heat
rising from chest to head, then throbbing pain in head. The characteristic neuralgias of Glon. are
accompanied with much throbbing, and are often < at night, preventing sleep. Supra-orbital
neuralgia, pulsating; retinal congestion from exposure to strong light. Facial neuralgia, extending
through head. Cardiac neuralgia (angina pectoris) with radiating pains.
Guernsey, with his usual graphic terseness, says that G/on. is suited to "Troubles of the head in
type-setters, and in men who work under a gas-light steadily, so that the heat falls on the head;
bad results from sunstroke; can't bear any heat about the head; can't walk in the sun, must walk
in the shade or carry an umbrella; can't bear heat from a stove; great vertigo on assuming an
upright posture, from rising up in bed, rising from a seat, &c. Heat in the head; throbbing
headache." The great sensitiveness to the least jar, which is a very marked feature of the G/on.
headache, causes the patient to carry his head very carefully in order to avoid the chance of it.
The headache is in the whole head and every part—forehead, vertex, occiput. Many pains appear
in occiput and base of brain; gnawing in occiput; sore pain; pressure; severe pain in occiput,
extending to eyes and temples; sensation as if something were moving in nerves from back of
neck upward to head. The eyes may be fixed or protrude; aversion to bright light; black spots
before sight. Face flushed or pale. Climacteric disturbances.