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Materia Medica

Kalium Permanganatum

Permanganate of Potassium
4 sectionsBoericke · 4

Essence

Prologue
Boericke

Permanganate of Potassium (KALI PERMANGANICUM)

  • Intense irritation of nose, throat, and larynx.
  • Diphtheria.
  • Dysmenorrhoea.
  • Bites of serpents and for other animal poisons.
  • Septic conditions; tissues infiltrated with tendency to sloughing.
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Throat

Throat
Boericke
  • Swollen and painful.
  • Everything hawked up streaked with blood.
  • Posterior nares painful.
  • Muscles of neck feel sore.
  • Swollen uvula.
  • Fetor of breath.

Respiratory

Respiratory
Boericke
  • Bleeding from nose.
  • Nasal discharge.
  • Smarts and irritates.
  • Constrictive, smarting sensation in throat.
  • Larynx feels raw.
  • Short, hacking cough.

Posology

Dose
Boericke
  • Locally, 1 dram to a quart of water, to correct fetor in cancer, ulcer, ozaena, and other foul odors.
  • Also as an injection in leucorrhoea and gonorrhoea.
  • Internally, 2x dilution in water.
  • Saturated solution locally in eruption of smallpox.

Potassium Permanganate for Morphine Poisoning.--Potassium permanganate is recognized as being the most effective chemical antidote in cases of morphine or opium poisoning, acting directly on the morphine and oxidizing it to less toxic substances. To be effective the permanganate must come in direct contact with the opium or morphine in the stomach; hypodermatic or intravenous injections are absolutely useless, as the salt would be decomposed by the blood serum at once. The approved treatment is administration of two to five grains of potassium permanganate in dilute aqueous solution as soon as possible after the poison is taken, this amounts to be increased if very large doses of the poison have been taken. Washing out the stomach with a quantity of 1 to 500 solution of permanganate is also recommended, using at least a pint of this solution either by a stomach pump or by enforced vomiting. Permang of Potash counteracts effects of alkaloids of many poisonous plants. Owing to its oxidizing powers if given before the alkaloid has been absorbed (Dr. Chestnut in Dept of Agriculture).

Classical Posology

Acute
  • 30C or 200C · repeat every 1–4 h depending on intensity
  • Stop on improvement · reassess in 24–48 h
  • For sensitive / elderly / paediatric: prefer LM1 or 30C
Constitutional
  • 200C or 1M single dose · wait 4 weeks
  • Alternative: LM1 daily × 10 days · ascend on retest
  • Hering's-Law follow-up adapts the next script
Citations: Organon §246 (interval / repetition) · §161 (plussed water) · §282 (LM ascension) · Kent on selection · Vithoulkas on second prescription. Open Repertify for the case-specific dose with the rule cited inline.
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