Morphinum and salts

Profound depression. Irritable, fault-finding, hysterical. Shock induced by terror. Dream-like state.

Excitement.—Could not describe her symptoms for tears and sobs—Emotions very

easily excited—Sad; melancholy; mute despair.—Great anxiety; thought she was going to

die —Anxious, restless, ran about the room.—Delirium like delirium tremens.—Illusions with

hypochondriacal mood; sees brilliantly coloured birds; hears voices; have a sensation of sitting in

wet; perceive various odours; thinks he will die; thinks he sees his own burial; that persons about

• ▸him are growing larger.
• ▸—Terror, cried out in great alarm.
• ▸—II|-humour.
• ▸—Irritable, wants to be

alone.—Flow of ideas rapid and pleasant; but without control of the will; like the condition of

dreaming.—Incapable of thinking or fixing mind.—Stupefaction; coma.

Vertigo from the least movement of the head. Headache with sensation of being "wound-up". Bursting pain; head drawn back.

After a nap head dull and confused as from disordered stomach, < by vinegar, < after

eating, compelled to lie down.—Giddiness and drowsiness; everything turns round.—Dull

pain.—Something shot to the head like lightning the instant the injection took place.—Brain feels

tense as though wound up tightly —Vertigo from least motion of head (caused by Morphinum;

• ▸verified by a cure with Morph.
• ▸mur.
• ▸500).
• ▸—Head dull; heavy as lead; hot.
• ▸—Headache: sudden;

intense; pressive; throbbing like a pulse, as if head would burst; in forehead; intolerable r. side;

in occiput.—Headache with drowsiness.—Tensive sensation, as if skull too small for brain;

reading, writing, thinking very difficult—Head drawn backward.

• ▸Bluish, drooping lids.
• ▸Itching of eyes.
• ▸Delusion of vision on closing eyes.
• ▸Starting, injected; diverging strabismus.
• ▸Pupils unequally contracted.
• ▸Look unsteady.
• ▸Ptosis.
• ▸Paresis of recti interni.

Eyes: staring; glistening; sparkling; injected; fixed; sunken; lustreless; feel too small

for sockets——Look becomes unsteady.—Ptosis.—Paresis of internal recti; diverging

• ▸strabismus.
• ▸—Eyeballs protrude.
• ▸—Nystagmus.
• ▸—Pupils: dilated; contracted to a minimum;

unequally contracted.—Sight: dim, blurred; obscured by fogs; double with disturbed

accommodation and frequently lachrymation—Delusion of vision on closing eyes, sees a man

standing at foot of bed; the room seems full of white and coloured babies.

Left ear throbs painfully; better, heat. Seems to hear circulation all over body.

• ▸Severe pain in |.
• ▸ear with pain at side of 1.
• ▸eye all day.
• ▸—Ringing; surring; roaring;

tinnitus.

Sneezing in paroxysms. Itching and tingling on end of nose.

Sneezing; in paroxysms; coryza.—Tickling in nose, cesophagus and larynx as before a

sneeze.—Intense itching, tingling, numb feeling on end of nose, rubs it constantly.

Dusky red or pallid lividity of face, lips, tongue, mouth or throat.

Heavy; confused; wild; haggard expression.—Face: intensely flushed; puffed; livid;

cyanotic.—Trismus, teeth clenched.

• ▸Very dry.
• ▸Tongue dry, brown violet in middle.
• ▸Thirst.
• ▸Loss of appetite, with aversion to meat.

Tongue: dry, brown; red; tip, margins, palate scarlet, tongue violet in middle; at

times trembles on putting it out.—Mouth: very dry; dry with thirst, nausea, vomiting, aversion to

meat; pastry; bitter, sticky.—Discharge of watery saliva from mouth.—Made a strange noise with

his mouth.—Speech: hasty; stammering; embarrassed and feeble.

Dryness and constriction in throat——Burning back of fauces.—Paralysis of pharynx,

swallowing almost impossible.—Jugular veins swollen, carotid arteries pulsating.

Dry and constricted. Pharynx paralyzed, swallowing almost impossible; better hot drinks, worse solids.

Nausea incessant and deathly, faintness, constant retching. Vomiting of green fluid. Nausea and vomiting on rising up.

Loss of appetite —Great thirst; burning.—Eructations: violent; with much acid

mucus.—Nausea, faintness, constant retchings, with alternate flushes of heat and cold.—Nausea

with drowsiness.—Vomiting: green matter; sour, bright green fluid; bitter, greenish water.—Pain

in stomach < by eating.—Pain in stomach, umbilicus, and bladder —Constriction; pressure;

cramp: colic; crawling in stomach.

Distended. Acute pain in abdomen and along spinal column. *Tympanitis.

Pain in umbilical region.—Distension.—Acute pain in abdomen, and along spinal

column, on every inspiration —Colic > turning on back in morning.

Diarrhoea watery, brown, or black with horrible tenesmus. Constipation; stools large, dry knotty, with tendency to bruise and fissure.

Diarrhcea (the acetate generally produced diarrhoea); watery; with horrid

tenesmus, straining and burning in rectum, almost causing frenzy.—Constipation for a long

time.—Stool retained.—Indolent evacuation of a little feeces with painful urging.

Paresis of bladder.—Suppression of stool and urine.—Ineffectual

efforts —Strangury.—Urine: turbid and slimy; diabetic—Albuminuria.

• ▸Paresis of bladder.
• ▸Strangury. Slow and difficult urination.
• ▸Retention of prostatic hypertrophy.
• ▸Uraemia, acute and chronic.

Amenorrhcea.—Menses too profuse; and too

early.—Sterility—Sexual desire at first increased, afterwards abrogated.

Impotency. Pain in right spermatic cord, (Oxal ac).

Impotency.—The sexual excitement, voluptuous sensations and

• ▸erections are incomplete or do not occur.
• ▸—Pain in genital and urinary organs, esp.
• ▸r.
• ▸spermatic

cord.—Diminished desire.

• ▸Faint and struggling for breath diaphragmatic paralysis; hiccough; dyspnoea, paroxysmal, on first falling asleep (Lach; Grindel).
• ▸Cheyne-Stokes respiration.
• ▸Chest tight.
• ▸Pain in middle of sternum.
• ▸Dry, hard, teasing, exhausting cough, worse at night.
• ▸Strangling cough, with viscid mucus sputum; thin, scanty, but sounds loose and abundant.

Hoarseness.—Breathing: stertorous; difficult; slow; thoracic breathing

entirely suspended.—Struggling for breath.

Alternation of tachycardia and bradycardia. Cardiac muscular tissue is intact, even if severely exhausted. Pulse small, weak, dicrotic.

Chest tight, breathing difficult, asked to be raised, saying she felt as if she were

dying.—Pain in middle of sternum.—Ill with an indescribable sensation, worse than any pain,

behind lower half of sternum.

Palpitation.—Violent throbbing in heart and carotids —Congestions of head,

palpitations of heart; starts in fright if approached; touch = cramp and twitchings.—Pulse small,

weak; dicrotic.

Pain along spine. Weakness of loins. Aching across lumbo-sacral region; cannot walk erect (Cimicif).

• ▸Stiff-neck.
• ▸—Great pain in back.
• ▸—Pain extending along spine.
• ▸—Pain and

twitchings all down spine.—Weakness of the loins.

Stiffness and pain in arms after sleep.—Twitchings, tremblings.—Fingers

numb and both thumbs firmly drawn into palms.

Gait insecure; tottering, staggering.—Legs swollen—Cramps in several

muscles.—Wandering, sharp pains in legs and feet; numbness of legs and feet with falling on

attempting to stand.—Her legs were twitched up and she begged that they might be held, as she

could not keep them quiet; it felt as if there were worms in them.—Icy coldness of |. sole as if

standing on oil-cloth.

24. Generalities—Sudden attacks of fainting —Numb feeling all

over.—Restlessness.—Convulsions.

Staggering gait. Numbness.

• ▸Livid; purple spots; zoster-like herpes.
• ▸Itching.
• ▸Skin lost its elasticity.
• ▸Urticaria appearing at climaxis.

Skin deathly pale.—Purple spots on body.—Skin lost its elasticity—Eruption like

zoster, but without pain.—Itching: constant; violent; all over; nose, neck, loins, inside thighs.

Yawning, drowsy; prolonged, deep sleep, Sleepless; restless sleep, with frequent startings. Sleepy, but cannot sleep.

• ▸Yawning.
• ▸—Heaviness; drowsiness.
• ▸—Prolonged deep sleep.
• ▸—Half waking, half stupid

condition, with perfect ability to think of different things though at the same time busy with

confused fantasies; during this slumber limbs stiff and immovable, could only be moved by very

• ▸great exertion of the will.
• ▸—Heavy sleep with red cheeks.
• ▸—Sleepless.
• ▸—Restless sleep with

frequent startings.—Sleep restless with headache, fever, and itching of skin.—Dreams: pleasant;

frightful.

Chills. Icy coldness. Burning heat; profuse sweat.

Chills and rigors.—Icy coldness; general; of extremities; of 1. sole-—Heat: burning;

itching; cheeks hot and flushed.—Sweat: profuse; cold, clammy; viscid; colliquative.

• ▸Chorea.
• ▸Constipation.
• ▸Convulsions.
• ▸Eyes, affections of.
• ▸Headache.
• ▸Irritation.
• ▸Jaws,

• ▸clenched.
• ▸Lightning-stroke.
• ▸Neuralgia.
• ▸Palpitation.
• ▸Sleep, disordered.
• ▸Strabismus, divergent.

• ▸Trismus.
• ▸Tympany.
• ▸Vertigo.
• ▸Vision, illusions of.

Characteristics——Morphia is the alkaloid of Opium, which contains the most characteristic

properties of the drug. The alkaloid itself, the Acetate, the Muriate, and the Sulphate have all

been used as pain-deadeners and sleep producers, but I do not find it practicable to attempt to

distinguish between them, since the particular salt given has not always been mentioned.

Alkaloids do not act in the same way as ordinary bases in their union with acids; the alkaloid

does not displace any of the molecules of the acid; a molecule of acid is simply added to a

molecule of alkaloid and not integrated with it. The distinction therefore between salts of

alkaloids is less than between salts of metals, &c. I have included effects of all in the Schema; it

is probable that the symptoms of any one of them will be sufficient to indicate any other. Rufus

• ▸L.
• ▸Thurston (H.
• ▸P.
• ▸, xv.
• ▸563) records a short but very important proving of Morphinum ona

patient who took a grain for sleeplessness. Among the symptoms was this, which he italicised:

• ▸"Vertigo from the least movement of the head.
• ▸" Not long after, Skinner (H.
• ▸P.
• ▸, xvi.
• ▸123) had a

case of vertigo with tendency to fall forward and with this symptom: "Becomes unconscious and

all becomes dark, < by movement of any kind, especially of the head, and by eating and

• ▸drinking.
• ▸Morph.
• ▸mur.
• ▸500 (F.
• ▸C.
• ▸) cured the case.
• ▸C.
• ▸M.
• ▸Boger (H.
• ▸P.
• ▸, xvi.
• ▸295) cured with

• ▸Morph.
• ▸sulph.
• ▸c.
• ▸m.
• ▸this case: Miss M.
• ▸, 22, dark, spare.
• ▸Headache with sensation of being wound

up tight. Sleepiness and numbness of lower extremities. /ntense vertigo on least motion of head.

Thus both the Muriate and the Sulphate availed to cure a symptom produced by the plain

alkaloid. In Thurston's case there was also the "wound-up" headache, which is confirmed by

Boger's cure as another note of Morph. Another feature of Thurston's case was sudden faintness.

The same symptom was produced, by one-eighth of a grain of the Su/phate, in a case reported by

• ▸E.
• ▸V.
• ▸Ross (H.
• ▸P.
• ▸, xvi.
• ▸524): "Spells of feeling faint come on suddenly, with great anxiety;

thought she was going to die." In the same case this peculiar symptom appeared: "Delusion of

vision on closing eyes, sees a man standing at foot of bed. The room seems full of white and

coloured babies." In my experience the Acetate has produced much more violent gastric

symptoms than the Muriate, but not different in kind. Green vomit is a constant effect.

Restlessness and hyperesthesia are prominent symptoms: restlessness of legs, wants them held;

feels as if worms in them. Trembling, twitching, jerking, and convulsions; even tetanus. This is

marked in the clenching of the jaws. Morphia habitués have extreme susceptibility to pain, and

Morph. is indicated in neuralgia where the pains are so violent as to threaten convulsions; pain

causing twitching or jerking of limbs. Violent and sudden neuralgic pains (as well as sudden

fainting). Morph. is just as susceptible emotionally as to pain; "Cannot describe symptoms for

• ▸tears and sobs.
• ▸" The head is very heavy and hot; drowsiness.
• ▸The sleep symptoms of Morph.
• ▸are

• ▸not distinguishable from those of Opium.
• ▸Intense drowsiness.
• ▸Deep sleep.
• ▸Half sleeping state:

"He lay in a half-waking, half-stupid state, but with perfect ability to think of different things,

though at the same time he was busy with confused phantasies; limbs stiff." On the other hand

there is sleeplessness and restless sleep with starting up. Dreams may be pleasant or frightful.

• ▸The symptoms are: < By eating.
• ▸< By movement.
• ▸< By (slightest) movement of head.
• ▸< After

sleep (head dull, vertigo as from disordered stomach, after a nap). < In morning (pain in head on

• ▸waking > on moving about).
• ▸< By vinegar.
• ▸> By coffee.
• ▸Morph.
• ▸cured nervous spasms brought

on by lightning-stroke, the spasms being < by any exposure to heat, > by cold; was compelled to

go to a cool place Peculiar sensations are: Tensive sensations in head as if skull too small for the

brain. As if brain wound up. Something shot to head like lightning the instant the injection took

• ▸place.
• ▸Sight as if obscured by a fog.
• ▸Tickling of nose and tip of nose.
• ▸Tongue as if thick.
• ▸Teeth as

if clenched. Indescribable sensation behind lower half of sternum. As if worms in legs.

• ▸Antidote to: Electricity (Morph.
• ▸acet.
• ▸, see ELECTRICITAS).
• ▸Antidoted by: Avena,

• ▸Atrop.
• ▸, Bell.
• ▸, Strong Coffee; Aco.
• ▸and Ipec.
• ▸especially useful for secondary effects.
• ▸[Keaney (1.

• ▸P.
• ▸, xv.
• ▸195) cured with one dose of Sul.
• ▸c.
• ▸m.
• ▸(Swan) a man who had taken two grains of

morphine daily for fifteen years.] /nimical: Vinegar (it increases the painful symptoms, vertigo,

• ▸&c.
• ▸).
• ▸Compare: Op.
• ▸, Codein.
• ▸, Apomorph.
• ▸In excessive sensibility, Aco.
• ▸, Cham.
• ▸Weeps in telling

• ▸symptoms, Puls.
• ▸Vertigo on least movement of head, Mosch.
• ▸(Mosch.
• ▸has also vertigo from

movement of eyelids). < By movement, Bry. (cats and other felines, and fowls, are insensible to

• ▸Morph.
• ▸(H.
• ▸W.
• ▸, xxvi.
• ▸334; xxix.
• ▸532) as rabbits are to Bell.
• ▸)

Third to sixth trituration.

An Alkaloid of Opium

• ▸Morphine bears the same relation to Opium as Atropine to Belladonna-i.
• ▸e, represents its nervous side.
• ▸It is less stimulating, less convulsant, and more decidedly hypnotic.
• ▸Constipates less and affects contractility of the bladder more.
• ▸It is less diaphoretic and more pruritic.

• ▸Restlessness and hyperethesia; trembling, twitching, jerking, convulsions.
• ▸Extremely susceptible to pain.
• ▸Pain causes twitching and jerking of limbs.
• ▸Violent and sudden neuralgic pains and sudden fainting.
• ▸Delirium, melancholic in character.
• ▸Neuralgias intensely painful, left supraorbital; right intercostal, better from heat; multiple neuritis.
• ▸Sore feeling all over.
• ▸Bed feels too hard.
• ▸Aggravation after sleep (Lach).
• ▸Neuralgia after zoster (Mezer).