Natrium Nitricum

• ▸Ringer and Murrell (Lancet, November 3, 1883—C.
• ▸D.
• ▸P.
• ▸) administered ten

• ▸grains of Na.
• ▸nirs.
• ▸, dissolved in an ounce of water, to fourteen men and four women.
• ▸To twelve

men and four women it was given in five-gr. doses. In almost all it produced alarming symptoms

• ▸of the apoplectic order.
• ▸A cat had 4 c.
• ▸c.
• ▸of a 10 per cent.
• ▸aqueous solution injected under the

• ▸skin, and died of the effects.
• ▸Collischorm (quoted H.
• ▸P.
• ▸, x.
• ▸469) relates two cases of accidental

poisoning with Nat. nitros. (1) The first patient was affected with: Diarrhoea and fainting, bitter

eructations, heavily coated tongue, and on the chest an eruption like syphilitic roseola. Traces of

albumen in urine. During the night, copious alvine discharges with faintishness. The following

• ▸day, intense cyanosis.
• ▸Urine dark yellow, containing copious urates.
• ▸Next day he took 2.
• ▸5 grin.
• ▸;

cyanosis diminished and the measly eruption spread all over the body except the face. (2) The

second patient had the cyanosis, diarrhoea, and faintings in an aggravated form so that collapse

• ▸threatened.
• ▸Strong Coffee and omission of the drug removed the symptoms.
• ▸< Motion.
• ▸> Lying

down. The concomitance of fainting with other affections may prove a keynote: "Copious liquid

stools at night with faintness."

Thought she would have died.—So much upset she feared she would never get over it.

The blood became colour of cherry juice; white corpuscles increased, red

diminished; watery constituents increased.—Weakness, disinclined for exertion.—Exhaustion,

• ▸esp.
• ▸in knees, during a walk (after a slight venesection).
• ▸—Exhaustion < every motion, esp.
• ▸going

up stairs.

• ▸Dull.
• ▸Indisposed to mental and bodily exertion.
• ▸Pressing inward pain.
• ▸Otalgia.
• ▸Inward pressing in malar bones.
• ▸Nosebleed.

Giddy, as if he would become insensible; lips, face, hands became blue, had to lie

down half an hour before he dared move.—Face and head seemed swollen throbbed violently till

she thought they would burst—Head felt as if it would split in two.—Terrible headache, < on

motion, esp. going up stairs.

Pain in r. ear, as if in drum; with sensation of binding up in ears.—Otalgia: in evening;

with warmth in ear, coldness of r. concha, burning heat of |., which extends beyond the temple.

Face lips, hands turned blue.—Lips turned black and throbbed for hours.—Deadly pale.

Some dull stitches back of throat on drawing air through nose (evening, in bed).

Sour risings. Aversions to coffee. Flatulence, with pressure in pit of stomach and pain in chest; worse motion, better eructation.

Coppery taste on lips and tongue.—Acid taste.—Appetite

diminished.—Repugnance to coffee.

Bitter eructations.—Feels very sick, but did not actually vomit.—Nausea and

• ▸eructations.
• ▸—Vomiting (two cases from 5-gr.
• ▸doses).
• ▸—The medicine kept rising, so he could not

keep it down.—Stomach firmly contracted (cat).

Abdominal muscles painfully contracted towards the spine. Distended. Difficult stool; feels as if more remained to pass.

Constipation: féces of a large size; the stool is discharged with difficulty,

slow, and with the sensation after the stool as if the féces were still remaining.—Stool always

consisted of isolated fécal masses, evacuated with great exertion; during last days of proving

constant desire to go to stool.—Stool indolent, only after effort, leaving sensation as if more to

follow.—Stool retarded one day.

Bladder firmly contracted (cat).—Urine: dark yellow; copious urates; trace

of albumen; methemoglobin.

Pain in region of heart. Pulse slower and softer.

Pressive pains below outer part r. pectoral muscle, as if between and on ribs, on deep

breathing, whilst sitting bent over.

Heart came on beating very fast; he throbbed all over.—L. ventrical contracted, r.

dilated (cat).—Blood very dark, almost like treacle (cat).

24. Generalities—Took all his strength away.—Trembling sensation all over and suddenly fell

on the floor—The women were more severely affected than the men.—Ten minutes after the dose

felt a trembling sensation all over and suddenly fell on the floor; whilst lying there she perspired

freely; face and head felt swollen, throbbed violently; felt sick —Faintness, nervousness.—Went

off in hysterics, could not hold a limb still.

Rash like roseola syphilitica on chest, measly, spreading to abdomen and thighs,

covered gradually all the body except the face.

Second trituration, also watery solution; 1 dram of salt to 8 oz water. Dram doses.