Nicotin. has had a very heroic proving by Falk, Wochenfeld, Wertheim,
Schroff, and Reil. Very violent tonic and clonic spasms were produced; indistinctness of senses;
loss of consciousness. Peculiar symptoms and sensations were: Great sensitiveness of eye to
light, along with indistinct vision. Aura in upper jaw. As though a sharp brush had been drawn
through cesophagus to stomach. Disagreeable sensation extending upwards and downwards from
stomach. Emptiness and faintness in stomach. Coldness extends from tips of fingers and toes
over trunk; and warmth streams into them from the stomach. Jerking respiration.