Pyrogenium

John Drysdale was the first, in 1880, to suggest the use of this substance as a

medicament (On Pyrexin or Pyrogen as a Therapeutic Agent, Bailli¢re, Tyndale & Cox). Burdon

• ▸Sanderson has stated (B.
• ▸M.
• ▸J/.
• ▸, February 13, 1875) that "only liquids which contain bacteria or

have a marked proneness to their production" are capable of setting up pyrexia. This remark

struck Drysdale, and though, of course, he could not endorse the "only" of the statement—many

drugs known to homeeopaths set up fever—he saw that the fact might be turned to account.

Sanderson further defines Pyrogen as "a chemical non-living substance formed by living

bacteria, but also by living pus-corpuscles, or the living blood- or tissue-protoplasms from which

these corpuscles spring." In Sanderson's experiments with Pyro. the following effects were

observed. (/) From a non-fatal dose: The animal shivers and begins to move about restlessly.

The temperature rises from 2° to 3° C., the maximum being reached in three hours. Thirst and

vomiting come on, followed by feculent and thin mucous, and finally bloody diarrhoea and

tenesmus. In five hours these symptoms begin to subside, and the animal recovers with

wonderful rapidity. When death occurs it is from heart failure. In non-fatal cases with gastro-

enteric symptoms the temperature gradually rises for four hours, and as gradually subsides: in

fatal cases it rises rapidly to 104° F., then rapidly declines to below normal. (2) From a fatal

dose: There is intestinal hemorrhage, purging, collapse, and death. After death extravasations of

blood are found in heart, pleura, and pericardium; the spleen is enlarged and full of blood.

Mucous membrane of stomach and small intestines is intensely injected with detachment of

epithelium and exudation of bloody fluid, which distends the gut. The blood is dark, the

corpuscles being in clumps instead of rolls, and many being dissolved in the liquor sanguinis.

White corpuscles partially disintegrated. Drysdale prepared a tincture of Pyro.—which he

preferred to call Pyrexin, since it is not a mere fever-producer: others have called it Sepsin; but

this is too close to Septiccemin, a name given to a related and perhaps identical nosode: I have

chosen to retain the name Pyrogen, by which the remedy is best known in homceopathy—and put

his own suggestion into practice. His success was very encouraging, but as he continued to use

the @ tincture and lowest attenuations the difficulty of keeping the preparation was not small;

and the remedy did not come into extensive use till Burnett published his pamphlet on

Pyrogenium in Fevers and Blood-poisoning in 1888. Burnett used chiefly the 6th centesimal

dilution, which is perfectly harmless, and which will keep indefinitely. Heath, who made one of

the preparations used by Burnett, gave some of it to Swan, of New York, who ran it up into the

high infinitestmals. Much of the American experience is with Swan's attenuations, including a

• ▸proving by Sherbino (Med.
• ▸Adv.
• ▸, xxv.
• ▸369), whose symptoms I have marked (S) in the Schema.

• ▸The remainder of the symptoms of the Schema are for the most part clinical.
• ▸Yingling (H.
• ▸P.
• ▸,

x11. 402) collected symptoms from many reported cases, and arranged them with the symptoms

of the proving. (Yingling erroneously describes Pyro. as prepared from "pus from septic

abscess." This is Septiceemin. He refers, however, to Burnett's pamphlet and to cases cured with

• ▸Pyro.
• ▸, leaving the actual substance referred to not in doubt.
• ▸H.
• ▸C.
• ▸Allen, who published the

• ▸proving and most of the cases in Med.
• ▸Adv.
• ▸, rightly describes Pyro.
• ▸as a "Product of Sepsis").

Drysdale's original cases include a number in which threatened typhoid was averted, a case of

tabes mesenterica cured, and one of ulceration of the colon greatly benefited. Burnett's were

cases of fully developed typhoid all cut short at the height by Pyro. 6 given every two hours. In

his pamphlet is included a successful experience of Dr. Shouldham's with Pyro. 6 in two cases of

diphtheritic sore threat. I have had ample opportunity of observing the power of Pyro. over

typhoid fever, and typhoid and hectic states, including one of discharging abscess connected with

• ▸Pott's disease of the spine.
• ▸T.
• ▸M.
• ▸Dillingham reports (Med.
• ▸Adv.
• ▸, xxvii.
• ▸367) the case of a young

German Jewess who had been under treatment at various hospitals for Bright's disease, and at the

Hahnemann Hospital of New York among Others. To this she was readmitted on March 14,

1890, when she first came under Dr. Dillingham's care. The urine showed an enormous amount

of albumen and a variety of casts. Feet and legs greatly swollen, face puffy. Throbbing headache,

often accompanied by profuse nose-bleed, nausea, and vomiting; < motion and light; abnormally

bright eyes, widely dilated pupils. Be//. gave temporary relief; but on May 31st the condition was

desperate. Dillingham then learned that the trouble dated from a large abscess resulting from a

lanced, badly cared-for felon of the left thumb. She was ill six weeks with this abscess, having,

as her doctors said, "blood poisoning." Soon after this her face and feet began to swell. On May

31st the condition was this: Feet, legs, and genitals greatly swollen. Frightful throbbing

headache, > by tight band constantly worn. > By heat; very fond of the hot bath. Headaches had

terrible aggravations lasting two to four days, during which time she could neither lie in bed nor

sit up, but was in constant motion, groaning and crying piteously for help. Pyro. cmm, Swan, one

dose was given, and no other medicine, although the patient on one occasion begged for

something to stop the pain. In the course of June she began to mend, and on October 20th was

discharged cured. In Sherbino's proving he was cured incidentally of a consciousness of the heart

and its working, and palpitation from least excitement or anxiety, < beginning to move;

congestion to head as if apoplexy would ensue. Cactus had done no good. Sherbino cured: (/) a

case of puerperal fever with Pyro., being led to its selection by the very high pulse rate. (2)

Relapse of typhoid, pulse 140, temperature 102° F.; both were normal in twenty-four hours. (3)

Young lady, 17, fever, aching bones, bed felt very hard. Numb, paralytic feeling. As the fever left

• ▸the pulse kept mounting up.
• ▸Pyro.
• ▸cmm, Swan, repeated as often as effect ceased, cured.
• ▸—Pyro.

is one of the germinal remedies of the materia medica. When once the idea of its essential action

is grasped an infinity of applications become apparent. As Drysdale put it, "The most summary

indication for Pyro. would be to term it the Aconite of the typhous or typhoid quality of pyrexia,"

and wherever poisoning by bacterial products (e.g., in the hectic of phthisis) is going on Pyro.

• ▸will be likely to do good.
• ▸Sepsis is the essence of the action of Pyro.
• ▸H.
• ▸C.
• ▸Allen gives this

indication for its use in septic states: "When the best selected remedies fail to relieve or

• ▸permanently improve "—analogous to the action of Pso.
• ▸and Su/.
• ▸in other conditions.
• ▸Also:

"Latent pyogenic process, patient continually relapsing after apparent simillimum." As Pyro. is a

product of carrion, the carrion-like odour of bodily emaciations, secretions, and excretions is a

keynote for its use. Other leading indications are: Restlessness; must move constantly to > the

soreness of parts. "Constipation, from impactum of feeces in fevers; stool large, black, carrion-

• ▸like.
• ▸" "Chill begins in back, between scapulz.
• ▸" "Severe general chill of bones and extremities.
• ▸"

In all cases of fever commencing with pains in the limbs," Swan. Pulse abnormally rapid, out of

all proportion to temperature." Pyro. 5, five drops in water night and morning, assisted in the

cure of a case of anal fistula in a case of Burnett's (On Fistula, p. 66). Under its action a sweating

at the seat which the man had had for many years disappeared; and the skin of his hands, which

• ▸were subject to dry eczema, assumed a much cleaner aspect.
• ▸J.
• ▸S.
• ▸Hunt (H.
• ▸W.
• ▸, xxxi.
• ▸54) reports

• ▸five cases of varicose ulcers, all of which healed quickly under Pyro.
• ▸Bellairs (H.
• ▸W.
• ▸, xxxiv.
• ▸298)

gave Pyro. 200 to an elderly woman who suffered for years with an ulcerated leg, which was

• ▸riddled with deep, burrowing wounds, extremely painful and discharging freely.
• ▸Hep.
• ▸, Sil.
• ▸, Ars.
• ▸,

• ▸Ham.
• ▸, did no good.
• ▸Under Pyro.
• ▸once or twice a day "a large boil" formed on the calf of the leg

and discharged its contents, after which the various ulcers healed up directly. The symptoms are

> by heat (drinking hot water; hot bath). > Tightly binding head. > Stretching out limbs; walking

about; turning over or changing position. Heart's action and cough < by motion. Eyeball <

• ▸moving eye.
• ▸Cough < motion and in a warm room.
• ▸< Sitting up in bed; rising.
• ▸(Cough > sitting

up; < lying down.)

• ▸Blood poisoning.
• ▸Ptomaine poisoning.
• ▸Sewer-gas poisoning.
• ▸Typhoid fever (remote

effects of). Dissecting wounds.

• ▸Full of anxiety and insane notions.
• ▸Loquacious.
• ▸Thinks he is very wealthy.
• ▸Restless.
• ▸Feels if crowded with arms and legs.
• ▸Cannot tell whether dreaming while awake or asleep.

Loquacious; can think and talk faster than ever before (S). Irritable (S).—Delirious on

closing eyes; sees a man at foot of bed—Whispers; in sleep.—Sensation as if she covered the

whole bed; knew her head was on pillow, but did not know where the rest of her body

was.—Feels when lying on one side that she is one person, and another person when turning on

the other side.—Sensation as though crowded with arms and legs —Hallucination that he is very

wealthy; remaining after the fever.

Relief from motion.

Painless throbbing. Fan-like motion of alae nasi (Lyc; Phos). Bursting headache with restlessness.

• ▸Staggers as if drunk on rising in morning (S.
• ▸).
• ▸—Dizziness on rising up in bed.
• ▸—Pains

in both mastoids, < r.; dull throbbing in mastoid region (S).—Great throbbing of arteries of

temples and head; every pulsation felt in brain and in ears; the throbbings meet on top of brain

(S).—Painless throbbing all through front of head; sounds like escaping steam (S).—Frightful

throbbing headache > from tight band.—Excruciating, bursting, throbbing headache with intense

restlessness (often accompanied with profuse nosebleed, nausea, and vomiting).—Sensation as if

a cap were on.—Rolling of head from side to side.—Forehead bathed in cold sweat.

• ▸Loud ringing, like a bell, 1.
• ▸ear (also r.
• ▸) (S).
• ▸—Ears cold.
• ▸—Ears red, as if blood would

burst out of them.

Nose-bleed; awakened by dreaming it and found it was so.—Sneezing: every time he

• ▸puts hand from under covers; at night.
• ▸—Nostrils closing alternately (S).
• ▸—Cold nose.
• ▸—Fan-like

motion of alz nasi.

Face: burning; yellow; very red; pale, sunken, and bathed in cold sweat; pale, greenish,

or chlorotic.—Circumscribed redness of cheeks.

• ▸Tongue red and dry, clean, cracked, smooth, as though varnished.
• ▸Throat dry, articulation difficult.
• ▸Nausea and vomiting.
• ▸Taste terribly fetid.
• ▸Breath horrible.

Tongue: coated white in front, brown at back; yellowish brown, bad taste in morning

(S).—Tongue: coated yellowish grey, edges and tip very red; large, flabby; yellow brown streak

down centre.—Tongue clean, smooth, and dry; first fiery red, then dark red and intensely dry;

smooth and dry; glossy, shiny; dry, cracked, articulation difficult —Taste: terribly fetid, as if

mouth and throat full of pus (produced by dose of Pyro. em, Swan); sweetish.—Breath horrible;

like carrion.

Coffee-grounds vomiting. Vomits water, when it becomes warm in stomach.

No appetite (S); or thirst.—Great thirst for small quantities, but the least liquid

was instantly rejected ——> Drinking very hot water.—Thirst and vomiting (dog).

Belching of sour water after breakfast (S)—Nausea and vomiting. —Vomiting:

persistent; brownish, coffee-ground; offensive, stercoraceous; with impacted or obstructed

• ▸bowels.
• ▸—Vomiting and purging.
• ▸—Vomits water when it becomes warm in stomach.
• ▸—> By

vomiting.—Urging to vomit; with cold feet——Stomach feels too full (S).

Intolerable tenesmus o both bladder and rectum. Bloated, sore, cutting pain.

Full feeling and bloating of abdomen (S).—When lying on I. side bubbling or

gurgling sensation in hypochondria, extending back to |. of spine (S).—Pain in umbilical region

with passage of sticky, yellow stool.—While riding in a buggy aching in |. of umbilicus; <

drinking water; > passing flatus down ward.—Soreness of abdomen so severe she can hardly

• ▸breathe, or bear any pressure over r.
• ▸side.
• ▸—Very severe cutting pains r.
• ▸side going through back,

< by every motion, talking, coughing, breathing deep; > lying on r. (affected) side; groaning with

every breath.

Diarrhoea; horribly offensive, brown-black, painless, involuntary. Constipation, with complete inertia (Opium); obstinate from impaction. Stools large, black, carrion-like, or small black balls.

Feculent and thin mucous, and finally bloody diarrhoea and tenesmus

• ▸(dog).
• ▸—Two soft, sticky stools, 8 to 9 a.
• ▸m.
• ▸—Involuntary escape of stool when passing flatus

(S).—Profuse watery, painless stools, with vomiting.—Stool horribly offensive, carrion-

like.—Stool very much constipated, large, difficult, requires much effort; first part balls, last part

natural, with streaks of blood; anus sore after (S).—Constipation: hard, dry accumulated feeces;

stool large, black, carrion-like; small black balls like olives.—Congestion and capillary stasis of

gastro-intestinal mucous membrane, shedding of epithelium, bloody fluid distending intestines

(dog).—(Sweat about anus removed; fistula relieved.)

Urine scanty; only passed twice in twenty-four hours (S).—Urine: yellow;

after standing, cloudy with substance looking like orange peel; red deposit on vessel hard to

remove; deposits sediment like red pepper (S).—Got up three times in night to urinate

• ▸(S).
• ▸—(Bright's disease of kidneys.
• ▸).
• ▸—Urine albuminous, containing casts; horribly offensive,

carrion-like.—Frequent calls to urinate as fever comes on.—Intolerable tenesmus of bladder;

spasmodic contractions, involving rectum, ovaries, and broad ligaments; [cured in a case of

Yingling's with Pyro. cm Swan (and higher); patient's next period came on naturally and

painlessly, whereas before menses had been painful and extremely offensive. |

• ▸Puerperal peritonitis, with extreme fetor.
• ▸Septicaemia following abortion.
• ▸Menses horribly offensive.
• ▸Uterine haemorrhages.
• ▸Fever at each menstrual period, consequent upon latent pelvic inflammation.
• ▸Septic puerperal infection.
• ▸Pelvic calculitis.
• ▸Inflammatory exudate.
• ▸Post-operative cases, with overwhelming sepsis.

Puerperal peritonitis with extreme fetor; a rotten odour.—Parts

seriously swollen (Bright's disease).—Menses horribly offensive; carrion-like.—Menses last but

one day, then a bloody leucorrheea, horribly offensive-—Heemorrhage of bright red blood with

dark clots.—Septiceemia following abortion; faetus or secondines retained, decomposed.—(Has

cured prolapsus uteri, with bearing down, > by holding the head and straining, as in the act of

• ▸labour.
• ▸).
• ▸—Abscess of 1.
• ▸ovary, acute throbbing pain, great distress, with fever and rigors (Pyro.

cm, Swan, produced an enormous flow of white creamy pus with general >).—Lochia: thin, acrid,

brown, or foetid; suppressed, followed by chills, fever, and profuse fetid perspiration.

Wheezing when expiring (S).—Cough; with large masses of phlegm

from larynx; < by motion; < in warm room; cough = burning in larynx and bronchi; = pain in

occiput; = stitching in small of back, only noticed in the chair; coughs up yellow sputa through

night (S).—Cough > sitting up, < lying down.—Expectoration: rusty mucus; horribly offensive.

• ▸Tired feeling about heart.
• ▸Palpitation.
• ▸Sensation as if heart were too full.
• ▸Always can hear her heart beat.
• ▸Pulse abnormally rapid,

out of proportion to the temperature pain in region of left nipple. Conscious of heart.

Pain in r. lung and shoulder, < talking or coughing.—Neglected pneumonia: Cough,

night-sweats, frequent pulse, abscess had burst discharging much pus of mattery taste (rapid

• ▸recovery under Pyro.
• ▸cm.
• ▸three doses).
• ▸—Chest sore, purple spots on it.
• ▸—Severe contracting pain

within lower sternum, sometimes extending to rib-joints and up to throat, as if oesophagus being

cramped.—Ecchymoses on pleura (dog).

Pain in region of |. nipple, as if in heart; increased action; pulse 120 (S).—Heart tired

as after a long run; increased action < least motion (S).—Every pulsation felt (painlessly) in head

and ears (S).—Sensation as if heart enlarged; distinct consciousness of heart (S).—Sensation as if

heart too full of blood.—Feels as if the heart were pumping cold water (Yingling).—Violent,

tiresome heart action.—Palpitation or increased action without corresponding increase of

temperature.—Palpitation < by motion.—Loud heart-beats; audible to herself and others —Could

not sleep for whizzing and purring of heart; when she did sleep was delirious.—Cardiac asthenia

from septic conditions—Ecchymoses on heart and pericardium (dog).

Throbbing of vessels of neck running up in waves from clavicles—Weak

feeling in back; stitching pain on coughing (S).

Pain in shoulder-joint; in front, passing three inches down arm (S).—Hands

and arms numb.—Hands cold and clammy.—Dry eczema of hands.

Aching above knees, deep in bones, while sitting by a hot fire; > by walking

• ▸(S).
• ▸—On going to bed aching in patella; > flexing leg (S).
• ▸—Aching above I.
• ▸knee as though bone

• ▸broken (S).
• ▸—Aching above knees in bones, > stretching out limbs (S).
• ▸—Tingling in r.
• ▸little toe as

if frost-bitten.—Feet and legs swollen (Bright's disease).—Numbness of feet.

24. Generalities—Cannot lie more than few minutes in one position, > change (S).—Debility in

morning, staggered on trying to walk (S).—Nervous, restless (S).—Aching all over, bed feels

hard.—Great muscular debility; rapid recovery in few hours (dog).

• ▸Throbbing in vessels of neck.
• ▸Numbness of hands, arms, feet.
• ▸Aching in all limbs and bones.
• ▸Bed feels too hard (Arn).
• ▸Great debility in the morning.
• ▸Soreness; better by motion (Rhus).
• ▸Rapid decubitus of septic origin.

Small cut or injury becomes much swollen and inflamed-discolored. Dry.

Skin pale, cold, of ashy hue.—Obstinate, varicose, offensive ulcers of old people.

Seems to be in semi-sleep. Dreams all night.

Slept awhile; woke to roll and tumble in every conceivable position (S).—Unable to

sleep for brain activity and crowding of ideas (S).—Restlessness > after sleep.—Cries out in sleep

that a weight is lying on her.—Whispers in sleep.—Kept awake by purring of heart—Dreams: of

various things; of business.

• ▸Coldness and chilliness.
• ▸Septic fevers.
• ▸Latent pyogenic condition.
• ▸Chill begins in back.
• ▸Temperature rises rapidly.
• ▸Great heat with profuse hot sweat, but sweating does not cause a fall in temperature.

"In all cases of fever commencing with pains in the limbs" (Swan).—Shivers and

begins to move about restlessly; temperature rises gradually and as gradually subsides

(dog).—Temperature rises rapidly to 104° F., and sinks rapidly from heart failure (dog, fatal

dose).—Chilly at times and a little aching; a little feverish (S).—After dinner, ache all over, chilly

• ▸all night, bed feels hard (S).
• ▸—After getting into bed, chilly, teeth chatter; woke 10 p.
• ▸m.
• ▸in

perspiration on upper part of body; > motion (S).—Feels hot as if he had a fever, but was only

• ▸99° F.
• ▸, feels like 105°.
• ▸—Cold and chilly all day.
• ▸—No fire would warm; sits by fire and breathes

the heat from it; chilly whenever he leaves it; at night when the fever came on he had a sensation

as if lungs on fire, must have fresh air, which gave >.—Frequent calls to urinate as soon as fever

came on; urine clear as water.—Every other day dumb ague.—Perspiration horribly offensive,

carrion-like; disgust up to nausea about any effluvia arising from her own body.—Cold sweat

over body.

• ▸Abscess.
• ▸Anus, sweating near.
• ▸Bed-sores.
• ▸Bright's disease.
• ▸Constipation.
• ▸Diarrhcea.

• ▸Dysentery.
• ▸Eczema.
• ▸Enteric fever.
• ▸Fistula.
• ▸Headache.
• ▸Heart, rapid action of; consciousness of;

• ▸failure of.
• ▸Hectic fever.
• ▸Indian continued fevers.
• ▸Influenza.
• ▸—Intestines, ulceration of; obstruction

• ▸of.
• ▸Labour: puerperal fever.
• ▸Ovary, abscess of.
• ▸Peritonitis.
• ▸Phthisis pulmonalis.
• ▸Ptomaine

• ▸poisoning.
• ▸Puerperal fever.
• ▸Pycemia.
• ▸Sepsis.
• ▸Spine, Pott's curvature of.
• ▸Tabes mesenterica.

• ▸Tuberculosis.
• ▸Typhilitis.
• ▸Ulcers, varicose; obstinate.
• ▸Varicosis.

Compare: Septiceemin (B. Sanderson says bacteria and pus cells produce the same

chemical result; Pyro. and Sept. may therefore he identical, but I think it best to keep them

• ▸distinct); Malar.
• ▸(the vegetable Pyrogen); Lach.
• ▸In typhoid with soreness, bed feels hard, Bap.
• ▸,

• ▸Arn.
• ▸, Rhus.
• ▸> Motion and stretching limbs, Rhus.
• ▸Cough < by motion and in warm room, Bry.

• ▸Uterine hemorrhage, Ipec.
• ▸("if Ipec.
• ▸fails when indicated give Pyro.
• ▸," Yingling).
• ▸Offensive

• ▸diarrhoea Pso.
• ▸Black stools, Lept.
• ▸Constipation, Op.
• ▸, Sanic.
• ▸, Pb.
• ▸Lochia thin, fetid, Nit.
• ▸ac.

Vomits water as soon as warm in stomach, Pho. Throbbing headache, Bell. Varicose, offensive

ulcers of old persons, Pso. Skin ashy, Sec. Suppuration, Hep.

Compare: Streptoccin (anti-febrile action; septic symptoms in infectious diseases). Rapid in its action, especially in its effect on temperature; Staphyloccin in diseases where the staphylococcus is the chief bacterial factor, as acne, abscess, furuncle; empyaema, endocarditis, etc. ; Sepin-A toxin of Proteus vulgaris, prepared by Dr. Shedd, same symptoms as Pyrogen, of which it is the main constituent; Echinacea; Carbo; Ars; Lach; Rhus; Bapt.

Complementary: Bryon.

Sixth to thirtieth and higher potencies. Should not be repeated too frequently.

The potencies prepared from Heath's 3d of decomposed beef have

been used by the author for many years against all forms of septic

fever and sequelae, when the symptoms agree. Violent chill intermingled with heat and sweat, or dry heat with marked aching in the

limbs ; restlessness, > by motion and heat. The sore bruised condition is as marked as in Arnica and Baptisia ; the aching in the bones

like Eupatorium, the restlessness, by motion and heat like Rhus.

Pains all aggravated sitting. Complaints come on from becoming

cold, and from cold damp weather, j

These features are found in h^#c fevers in the last stages of phthisis, as well as septic fevers. It aborts puerperal fever in a few hours

when clearly indicated. In cases of typhoid where there is the confusion like that found in Baptisia and the heal is too intense for that

remedy. Pyrogen should always be considered. When the temperature reaches 106® and there is great soreness and aching this remedy

will make great changes in a single day ; but if the pains are > by motion and heat it will abort the fever.

When the pulse is extremely high, and the temperature not correspondingly high this remedy will he useful. On the other hand, when

the pulse and temperature are out of rhythm either way this remedy

should be considered if the case is of septic origin. Great pain when

the flow from an open abscess becomes scanty. Violent burning in an

• ▸abscess (Ars.
• ▸, Anthr.
• ▸, Tarent.
• ▸C.
• ▸).

Offensivencss prevails extensively ; even putrid and cadaveric odors

of body, breath, sweat and discharges. Fevers from sewer gas poisoning ; erysipelas from infection and surgical fevers. It cures many

chronic complaints that date back to septic conditions. She has not

been well since a puerperal fever many years ago, is a good reason for

thinking of Pyrogen. ^

A young man of good inheritance suffered from blood poison and

made a poor recovery, and for several years was affected with abscesses in various parts. He was pale and sickly, rheumatic and stiff ;

at this time there was an abscess of the calf slowly forming. He took

Pyrogen and made a rapid and complete recovery. This time the abscess did not open. He has remained in good health now ten years.

It has cured Bright’s disease that could ‘be traced to septic origin-

It is a most useful remedy when there is threatening heart failure in

septic and zymotic fevers. Septic hiemorrhage, when the blood is

dark. It will often save life in the most dangerous and rapid septic

fevers.

Loquacity ; can think and talk faster than ever before, especially

during fever.

Irritable. Delirium and confusion of mind about his body and limbs

(Bapt,),

Sensation as though he covered the whole bed.

Knew her head was on the pillow, but did not know where the rest

ol the body was.

Feels when lying on one side she is one person, and another when

turning on the other side.

Sensation as though crowded with arms and legs.

These symptoms are much like Baptism^ but if the temperature runs

very high Baptisia will not meet the condition so well as l^rogen.

Violent congestion of the head zvith pressing pain and pulsation, >

by pressure. Copious sweat on the head. Pain in occiput on coughing ; in the morning on walking.

The eyeballs are sore to touch, on turning them outwards or upwards.

Septic bleeding from nose. Fan-like motion of alae nasi (Lyc.).

Face pale, sunken, and covered with cold sweat. Cheeks red and

burning hot.

The mouth is foul, and the taste putrid. The tongue is coated, and

• ▸brown.
• ▸Brown streak down the center.
• ▸Sordes on the teeth.
• ▸Putrid

odor from mouth.

Vomiting ; of bile, blood ; of putrid masses. Vomits water when

it becomes warm in the stomach. Stercoraccous vomiting. Coffee

ground vomiting. Thirst for cold drinks during chill and heat.

Distension and great sensitiveness of abdomen. Inflammation of

• ▸peritoneum, intestines and uterus, of septic origin.
• ▸Rumbling in bowels.
• ▸Pain on deep breathing.
• ▸Cutting, colicky pain.
• ▸Pain in right

side going through to the back < on every motion, talking and breathing ; > by lying on right side ; groaning with every breath.

Copious, liquid, putrid stools. Involuntary stool. Profuse, watery,

painless stool. Stool carrion-like. The difficult constipated stool also

like carrion in odor. Constipation with hard dry, black, putrid stools ;

small black balls like olives. Putrid bloody stools. Soft narrow stools

with great straining. Haemorrhage from bowels.

• ▸IJrine scanty or suppressed.
• ▸Red deposit, hard to wash off.
• ▸Albuminous urine containing casts.
• ▸Putrid urine.
• ▸Frequent calls to urinate as the fever comes on.
• ▸Intolerable tenesmus of the bladder ;

spasmodic contractions, involving rectum, ovaries, and broad ligaments

(case cured by Yingling). Involuntary urine and stool in septic fevers.

Uterine haemorrhage. Putrid y scanty lochia. Suppressed lochia.

Violent chill ; puerperal fever. Menses lasting one day, then bloody

leucorrhoea. Septic fever following abortion. Prolapsus of uterus.

Wheezing when expiring. Weak and husky voice, and hoarseness.

Cough with large masses of mucus from larynx, < by motion, and in

warm room. Cough causes burning in larynx and bronchi. Putrid,

thick, purulent expectoration. Cough < by lying, > by sitting up.

Bloody or rusty expectoration. Cough, with copious, offensive night

sweats. It is a great palliative in the last weeks of consumption. Abscesses in lung.

Heart failure in septic fevers, < by least motion. Every pulsation

felt in distant parts. Anxiety and sinking sensation in region of heart.

Distinct consciousness of the heart. Aching at the bifurcation of the

trachea. Oppression of chest and heart. Fulness in region of heart.

• ▸Feels as if the heart were pumpm]^ cold water (Yingling).
• ▸Palpitation.
• ▸, Loud heart , heats.
• ▸.
• ▸&nsatio|i of purring, of the heart .
• ▸Rapid,

irrepilar.,^ fluttering, pulse. ’ ...

Pulsation in the neck. Weak feding in the back. Stitching in back

on coughing.

Pain in all the limbs with great restlessness. Aching in bones all

over the lx)dy. Soreness of the -muscles and the bed feels hard, >*

• ▸by motion.
• ▸Cold extremities.
• ▸Numbness of extremities.
• ▸Hands and

arms numb. Hands cold and clammy. Pain in the thighs during chill

and fever. Pain in the knees and legs during chill and fever, ameliorated from walking, and from heat. Aching in legs while sitting, >

• ▸by walking.
• ▸Aching above knee as if bone were broken, > by stretching of limbs and motion.
• ▸Feet and legs dropsical.
• ▸Numbness of feet.

Skin pale, cold, of ashy hue. Obstinate varicose offensive ulcers of

old people. It has cured many old fever sores with putrid, thin, bloody

discharges. Carrion-like perspiration. Putrid odors of the body.

Must be covered in all stages. Chill ameliorated by warm bed. The

chill is quotidian ; it comes in the evening, generally at 7 p. M. The

periodicity is regular. Cold sweat on the body. Hot sweat with high

temperature. The sleep is full of frightful dreams. Persistent

thoughts prevent sleep. Suffocation in sleep. Cries out in sleep from

oppression of chest.

Aching: in bones; all over body as from a severe cold; with soreness of flesh, head

feels hard; > motion (S).—Cold extremities.—Numbness of hands, arms, and feet, extending over

• ▸whole body.
• ▸—Automatic movement of r.
• ▸arm and r.
• ▸leg, turned the child round from r.
• ▸to 1.
• ▸till

feet reached the pillow: repeated as often as she was put right (cerebro-spinal meningitis).