Thyreoidinum

Thyroiodine is now more generally named Jodothyrine, but I retain the former

• ▸as more convenient.
• ▸Hoenigschmied (Aerz.
• ▸Cent.
• ▸Zeit.
• ▸, No.
• ▸6, 1900, quoted A.
• ▸H.
• ▸, xxvii.
• ▸211)

says of it that it is present in only small quantities in the thyroid of the sheep. It is completely

free from albuminous substances, stable, and directly assimilated. The iodine exists in organic

• ▸combination, and Thyri.
• ▸contains 0.
• ▸003 parts of Jodine to every gramme.
• ▸The general effects of

the drug are—increased secretion of urine and corresponding loss of flesh. Hoenigschmied gives

two cases: (/) Labourer, 42, for several years had enlargement and induration of all lobes of

thyroid, the enlargement causing compression of the structures of the neck, dyspnoea, whistling

respiration, hoarseness, short, dry cough, vertigo. Thyri., 5-grain tablets, one every evening; at

the end of a week twice daily. After using twenty-five tablets the gland was smaller and softer;

the previously hard and resistant nodules were elastic; after two more weeks only remnants of

the goitre remained. (2) Man, 60, thyroid enlarged in all its lobes with a glandular cystic swelling

in the right one; dyspnoea, loud whistling breathing. Two, three, and at last four tablets were

given daily for two months, by which time the goitre had vanished, but the cyst was not changed.

(3) Man, 45, medium height, sedentary, suffered from obesity, vertigo, dyspnoea, weariness.

Pulse feeble, 76; functions normal; appetite and sleep good; weight 230 pounds. With increasing

doses of Thyri., up to ten tablets daily, the weight steadily went down to 160 pounds, activity

increasing in proportion. When the dose had reached four tablets daily the urine became very

abundant, but was free from albumen. The daily dose was increased one tablet every four days.

At one stage Fowler's solution of arsenic, four drops in wine, was given as well to prevent

Thyroidism.

Stupor, alternating with restless melancholy. Irritable, worse least opposition; goes into a rage over trifles.

Acute stupor alternating with restless melancholia at times could not be got to speak,

but would lie on floor with limbs rigid at other times would weep and undress herself; at times

dangerous and homicidal, would put her arms round the necks of other patients so tightly as

almost to strangle them; (in this case the insanity was primary and the myxcedema secondary;

both conditions were removed).—Evinced increased vivacity by quarrelling with another patient

about a trifling difference of opinion.—Depression.—Fretfulness and moroseness gave way to

cheerfulness and animation.—"All progressed cases of myxcedema show some mental aberration

which tends towards dementia, usually with delusions, the latter taking the form of suspicion and

persecution. Occasionally actual insanity is present in the form of mania and

insanity." —Delirium of persecution (three cases observed, one fatal, the result of taking Thyr. in

tablets to reduce obesity).—Sudden acute mania occurring in myxcedema, perfectly restored

mentally and bodily under 7hyr.—Mental aberration dating three years before onset of

myxcedema, subject to attacks of great violence, with intervals of depression and

moroseness.—State of idiocy; fearful nightmares.—Excited condition, lasting all the rest of the

day, grunting continuously and laughing in a way that was peculiar to herself—Very excited;

excited state followed by considerable depression.—For several hours in what can only be termed

a hysterical condition.—Profound depression.—Irritable and ill-tempered—Became a

grumbler.—Angry.—Had frights.

• ▸Feeling of lightness in brain.
• ▸Persistent frontal headache.
• ▸Eyeballs prominent.
• ▸Face flushed; lips burn.
• ▸Tongue thickly coated.
• ▸Fullness and heat.
• ▸Face flushed.
• ▸Bad taste in mouth.

Vertigo.—Feeling of lightness in the brain, scarcely amounting to giddiness.—Much

• ▸giddiness and headache for twenty-four hours.
• ▸—Awoke about 4 a.
• ▸m.
• ▸with sharp headache and

intense aching in back and limbs, which continued for three days and compelled him to keep his

bed.—Ever since taking the first thyroid [had had five glands altogether, at intervals] he had a

strange heavy feeling in his head, with vertigo and palpitation on stooping.—Headache (with

fever symptoms); disappeared on suspending treatment, reappeared seven days after

recommencing.—Fronto-coronal headache about two hours after each tabloid.—Persistent frontal

headache after taking one tabloid for four successive days.—(Constant headache, pains in occiput

• ▸and vertex.
• ▸).
• ▸—(Headaches in case of acromegaly.
• ▸).
• ▸—Headache.
• ▸—Headache and pains in

• ▸abdomen.
• ▸—Fresh growth of hair (many cases).
• ▸—Black hairs growing among the grey.
• ▸—In one

case of scleroderma and in one case of myxcedema the hair fell off permanently.—In a case of

myxcedema the patient lost all the hair of his head and face and had thick growth over his arms

and thorax; under 7hyr. the hair of the head and face grew again and that of the arms and chest

fell off.

Progressive diminution of sight with central scotoma (Carbon sulf).

(Prominence of eyeballs—exophthalmic goitre.).—Optic neuritis (in five persons, four

of them women, under treatment for obesity; no other symptoms of

thyroidism).—Accommodative asthenopia.

Moist patches behind ears heal up (case of psoriasis).—Hyperplasic median otitis with

sclerosis and loss of mobility of the ossicles (rapid amelioration—several cases).

Flushing: with nausea and lumbar pains; loss of consciousness, tonic muscular spasm;

immediate; with rise of temperature, and pains all over; suddenly became breathless and

livid.—Faintness, with great flushing of upper part of body and pains in back.—Swelling of face

and legs.—In lupus of face, tight sensation, heat, and angry redness removed.—Burning sensation

of lips with free desquamation.

Tongue became thickly coated.—Feverish and thirsty —Great thirst —(Ulcerated

patch on buccal aspect on |. cheek near angle of mouth.)

Dry, congested, raw, burning; worse left side.

Desire for sweets and thirst for cold water. Nausea worse riding in car. Flatulence, much flatus in abdomen.

Loss of appetite —Increased appetite with improved

• ▸digestion.
• ▸—Eructations.
• ▸—Dyspeptic troubles —Nausea, with flushing and lumbar pains.
• ▸—Nausea,

slight vomiting.—Slight nausea recurring on thinking of it.—Nausea soon after taking the

gland.—On five occasions the patient (a woman) vomited the thyroid.—Always felt a sensation of

sickness after the injections.—Sensations of faintness and nausea (after a few injections).—Feels

tired and sick.—Gastro-intestinal disturbance and diarrhcea.

Flatulence increased, followed later in the case by amelioration.—Headache and

pain in abdomen.

Diarrhcea; with gastro-intestinal disturbance.—Relief of constipation with more

natural actions.—Constipation.

Increased flow of urine.—Increased urination, usually with clear, pale

yellow secretion.—Slight trace of albumen found in urine—Albuminuria.—Diabetes mellitus;

caused and cured.

Increased flow; polyuria; some albumen and sugar. Enuresis in weakly children who are nervous and irritable (1/2 gr night and morning). Urine smells of violets, burning along urethra, increase of uric acid.

Increased sexual desire.—Six days after commencement of

treatment menstruation, which had been absent over a year, reappeared and continued profusely

(in several cases of myxcedema with or without insanity).—Menses profuse, prolonged, more

• ▸frequent; early amenorrhcea.
• ▸—(Painful and irregular menstruation.
• ▸).
• ▸—(Constant left ovarian pain,

and great tenderness).—Looks pale and feels ill—Pain in lower part of abdomen, headache and

sickness (in girl of sixteen, probably menstrual effort provoked by Thyr.; no catamenial flow

appeared).—Acts as a galactagogue when milk deficient; when the deficiency is associated with a

return of the menses it will suppress the latter—(Puerperal insanity with fever.).—(Puerperal

eclampsia. )

Dry, painful cough with scanty, difficult expectoration and burning in pharynx.

Slight attack of hemoptysis, followed by cough and signs of phthisis

• ▸at apex of |.
• ▸lung.
• ▸—(Voice became clear.
• ▸).
• ▸—Dormant phthisis; lighted up the disease in five cases.

• ▸Weak, frequent pulse, with inability to lie down.
• ▸Tachycardia (Naja).
• ▸Anxiety about chest, as if constricted.
• ▸Palpitation from least exertion.
• ▸Severe heart pain; Ready excitability of heart.
• ▸Heart's action weak, with numbness of fingers.

Death, with all the symptoms of angina pectoris.—On trying to walk

uphill died suddenly from cardiac failure-——While stooping to put on her shoes she "fainted" and

died in half an hour.—On one occasion, after exerting herself more than she had done for a long

time previously, "suddenly became extremely breathless and livid, and felt as if she was dying;"

> by rest in recumbent position and stimulants ——Two fainting attacks.—Frequent fainting

fits —-Complained occasionally of a feeling of faintness, not occurring particularly after the

injections.—One patient showed extraordinary symptoms after the injection; the skin became so

livid as to be almost blue-black. —Degeneration of heart muscle in animals.—A systolic cardiac

murmur was less loud after the treatment than before.—Sensations of faintness and

• ▸nausea.
• ▸—Palpitation on stooping.
• ▸—Weakness of heart's action.
• ▸—Tachycardia and ready

excitability of the heart persisting for several days after the feeding was stopped.—Pulse rose to

• ▸112.
• ▸—Relaxation of arterioles —(Rapid pulsation, with inability to lie down in bed.
• ▸).
• ▸—(Jumping

sensation at heart.)

Flushing, nausea, and lumbar pains, lasting a few minutes.—Stabbing pains in lumbar

region.—Intense aching in back and limbs, which continued for three days.—Flushing of upper

part of body and pains in back.—(Backache.)

After injection, to a great extent lost the use of her hands for two days;

recurred later, lasting a few hours.—Felt queer and unable to raise her arms (after injection,

another case).—Arms less stiff and painful (psoriasis).

Tingling sensation in legs—CEdema of legs appeared, and subsequently

subsided and continued to reappear and subside for a month.—Pain in legs.—Incomplete

paraplegia —Swelling of face and legs.—Feet repeatedly peel in large flakes, leaving a tender

surface.—Profuse flow of fluid from feet (in case of dropsy cured by 7hyr.).

24. Generalities—Malaise > by lying in bed.—Stooping = palpitation —Rest in recumbent

position > extreme breathlessness with lividity, felt as if dying —Myxcedematous patients are

always chilly; the effect of the treatment is to make them less so.—Loss of consciousness and

general tonic muscular spasm for a few seconds.—Fainting attacks (many cases).—Tremors,

• ▸quivering of limbs, complete unconsciousness.
• ▸—(Tetany.
• ▸).
• ▸—Epileptiform fit, after which he was

unconscious for an hour; next day felt better and warmer.—Malaise so great she refused to

continue the treatment.—A gitation.—_Incomplete paraplegia —Hysterical attack —(Hystero-

• ▸epilepsy with amenorrhcea.
• ▸).
• ▸—Nervous and hysterical, had to have nurses to watch her.
• ▸—Feels

• ▸tired and sick.
• ▸—Stabbing pains.
• ▸—Aching pains (many cases).
• ▸—Aching pains all over.
• ▸—Diffused

• ▸pains.
• ▸—Aching pains in various parts of body.
• ▸—Pains over whole body.
• ▸—Brawny swelling at

point of injection, followed by abscess of slow development.—Myxcedema removed (many

cases).—"A series of abscesses resulting from the injections, but probably originating from an

• ▸accidental abscess quite independent of them.
• ▸".
• ▸—A small abscess formed.
• ▸—Increased suppuration

in case of lupus.—Gained a stone in weight.—Lost weight enormously (many cases of

myxoedema).—Rapid gain of flesh and strength—Aneemia and debility.—Infiltration rapidly

absorbed (psoriasis).—Persons suffering from skin disease can bear much larger doses than those

• ▸suffering from myxcedema.
• ▸—(Acromegaly, headaches, and subjective symptoms.
• ▸).
• ▸—(Fractures

• ▸refuse to unite.
• ▸).
• ▸—A peculiar cachexia more dangerous than myxcedema itself.
• ▸—Syphilis

secondary and tertiary.

• ▸Rheumative arthritis with tendency to obesity, coldness and cramps of extremities.
• ▸Peeling of skin of lower limbs.
• ▸Cold extremities.
• ▸Aching pains.
• ▸OEdema of legs.
• ▸Trembling of limbs and entire body.

• ▸Psoriasis associated with adiposity (not in developing stage).
• ▸Skin dry, impoverished.
• ▸Cold hands and feet.
• ▸Eczema.
• ▸Uterine fibroids.
• ▸Browny swelling.
• ▸Swelling of glands of stony hardness.
• ▸Sluggish cases.
• ▸Jaundice with pruritus.
• ▸Ichtyosis, lupus.
• ▸Itching without eruption, worse night.

Flushing of skin.—Skin became so livid as to be almost blue-black.—Skin has

desquamated freely, but there has been no perspiration or diuresis.—Psoriasis; eruption extended

and increased.—(Psoriasis; redness and itching reduced; eruption separating and being shed in

great scales, angry, inflamed appearance completely gone.).—Moist patches behind ears heal

up.—Arms less stiff and painful; swelling diminished.—Crusts separated, leaving faint red skin;

eruption not nearly so painful—(Symmetrical serpigenous eruption; dark red; edges raised and

• ▸thickened.
• ▸).
• ▸—Lupus: tight feeling, heat, angry redness removed; suppuration increased.
• ▸—Eczema:

irritation of skin markedly allayed.—Scattered pustules of eczema mature quickly or

• ▸abort.
• ▸—(Teething eczema.
• ▸).
• ▸—(Syphilitic psoriasis.
• ▸).
• ▸—(Rupia.
• ▸).
• ▸—Scleroderma.
• ▸—Peeling of skin

beginning on legs and extending over whole surface; skin has since become comparatively soft

and smooth.—Peeling of skin of lower limbs, with gradual clearing (eczema).—Skin of hands and

feet desquamated.

• ▸Continual tendency to sleep —Awoke about 4 a.
• ▸m.
• ▸with sharp headache.
• ▸—Fearful

nightmares disappeared.—Insomnia.—Exited condition; could not sleep.

Flushing: with nausea; with loss of consciousness.—Always felt hot, and had a

sensation of Sickness after the injections.—Felt better and warmer.—Flushing of upper part of

body and pains in back.—Temperature never rose above 99° but she felt feverish and

• ▸thirsty.
• ▸—Temperature rose to 100° F.
• ▸, and remained there several days; pulse 112.
• ▸—Rise of

temperature; diaphoresis.—Profuse perspiration on least exertion.

Thyroiodinum.

Todothyrinum. Trituration.

• ▸Compare: Spongia; Calc; Fucus; Lycopus; Iodothyrine, (the active principle isolated from thyroid gland, a substance rich in Iodine and nitrogen, affects metabolism, reducing weight, may produce glycosuria.
• ▸Use cautiously in obesity, for a fatty heart may not be able to maintain the accelerated rhythm.
• ▸Milk contains the internal secretion of the thyroid).
• ▸Thymus gland extract (arthritis deformans; metabolic osteoarthritis, 5-grain tablets 3 times daily).
• ▸High potencies very efficient in exophthalmic goitre.

Crude Thyroid at times; better sixth to thirtieth potency. If the crude Thyroid is taken (two to three grains or more daily); the pulse should be watched. Must not be given in physiological doses where with feeble heart there is high blood pressure and not in tubercular patients.

Quivering of limbs; tremors.—Intense aching in back and limbs, lasting three

days.—Pains in arms and legs, with malaise —Skin of hands and feet

desquamated.—(Acromegaly, subjective symptoms. )

Dried Thyroid Gland of the Sheep

• ▸Thyroid produces anaemia, emaciation, muscular weakness, sweating, headache, nervous tremor of face and limbs, tingling sensations, paralysis.
• ▸Heart rate increased, exophthalmus and dilation of pupils.
• ▸In myxoedema and cretinism its effects are striking.
• ▸Rheumatoid arthritis.
• ▸Infantile wasting.
• ▸Rickets.
• ▸Delayed union of fractures.
• ▸In half grain doses twice a day over a considerable period said to be effective in undescended testicle in boys.
• ▸Thyroid exercises a general regulating influence over the mechanism of the organs of nutrition, growth and development.
• ▸Thyroid weakness causes decided craving for large amount of sweets.

• ▸Of use in psoriasis; and tachycardia.
• ▸Arrested development in children.
• ▸Improves the memory.
• ▸Goitre.
• ▸Excessive obesity.
• ▸Acts better with pale patients, rather than those of high color.
• ▸Amblyopia.
• ▸Mammary tumor. Uterine fibroid.
• ▸Great weakness and hunger, yet loses flesh.
• ▸Nocturnal enuresis. Agalactea.
• ▸Begin treatment early in pregnancy.
• ▸Dose 1 1/2 gr.
• ▸2 to 3 times daily.
• ▸Vomiting of pregnancy (give early in morning before patient gets up).
• ▸Fibroid tumors of the breast, 2x trit.
• ▸Dilates arterioles (Adrenaline contacts them).
• ▸Sensation of faintness and nausea.
• ▸Marked sensitiveness to cold Hypothyroidism after acute diseases, i.
• ▸e, weakness.
• ▸Easy fatigue, weak pulse, tendency to fainting, palpitation, cold hands and feet, low blood pressure, chilliness and sensitive to cold (Thyroid 1x3 times daily).
• ▸Has a powerful diuretic action in myxodema and various types of oedema.