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Materia Medica

Urea

8 sectionsBoericke · 2Clarke · 6
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Keynotes

Characteristics
Clarke

The failure of the kidneys to eliminate Urea from the blood leads to ureemic

intoxication, delirium, convulsions, and coma. On general indications Urea has been used in

medicine by both schools. Merck mentions that it is diuretic, and is used in cirrhosis of liver,

pleurisy, renal calculus. Allen cites from Mauthner two cases of renal dropsy with symptoms of

  • general intoxication in which Urea nit.
  • , gr.
  • i1.
  • , divided into three doses and given two hours

apart, cured brilliantly. Burnett has used both Urea 6 and Uric acid 6 in gouty eczema, "where

the gouty eczema has been the cutaneous outlet for the constitution." Burnett gave Urea in gouty

cases where the urine was thin and of low specific gravity; "it thickens the urine and gives great

  • relief to the patient.
  • " Arthur H.
  • Buch (Med.
  • Press, Aug 14, 1901) relates cases of tuberculosis

cured, on the plan originated by Harper, of Nottingham, with Urea in 20- to 30-grain doses three

times a day. Urea, Buch says, "is formed in the spleen, lymph and secreting glands, but

principally by the liver." Under the treatment, lupoid nodules disappeared; tuberculous glands

disappeared; tuberculous joints improved. No ill-effects of the treatment were noticed; "on the

  • contrary, the action has evidently been in many cases that of a nervous tonic.
  • " Villers (J.
  • of Hcs.
  • ,

iv. 403) examined the urine of an intensely neurasthenic woman, suffering from severe asthma

  • and found 4.
  • 5 per cent.
  • of Urea instead of the usual 2.
  • 5.
  • In order to find out the effect of Urea on

the healthy he took for five days Urea 15x., five drops thrice daily. He was then compelled to

stop by the severity of the symptoms. He gave the same dose to a patient, a woman. She begged

after a short time to be allowed to discontinue the medicine, as it affected her so painfully,

causing constant urging to urinate; much sediment in the urine; intolerable sensation in abdomen

and burning of the skin. The symptoms of Villers and this patient are marked (V) in the Schema.

Generals

Symptoms — Generalities
Clarke

General uneasiness; felt ill, poisoned (V).—Ureemia.—Acted as a nervous tonic

in tuberculous patients.

Abdomen

Symptoms — Abdomen
Clarke

In r. hypochondrium, a steady, dull sensation (V).—Intolerable sensation in

abdomen and burning of the skin (V).

Urinary

Symptoms — Urinary Organs
Clarke

Constant urging to urinate, beginning at root of penis (V).—Constant

urging, with much sediment in urine (V).—From bladder to her groins a fatiguing, tearing pain <

standing (V).—Profuse diuresis with rapid diminution of dropsy.—Albuminuria; bloody urine;

  • general dropsy; intermittent heart (boy, 7, Urea nit.
  • gr.
  • ii.
  • , taken in three doses at two hours'

interval, cured).—Delirium, nose-bleed, urine brown, very albuminous; cedema of pudenda;

ascites; pulse small, slow; attacks of suffocation (girl, 6, Ur. nit. as above; urine increased;

swelling decreased; albumen disappeared).

Clinical

Clinical
Clarke
  • Albuminuria.
  • Diabetes.
  • Dropsy.
  • Eczema, gouty.
  • Gout.
  • Liver, cirrhosis of.

Tuberculosis. Ureemia.

Relations

Relations
Clarke
  • Compare: Urinum, Uric acid, Thios.
  • , Urt.
  • urens.
  • Diuresis, Thyr.
  • Tuberculosis, Tub.
  • ,

Bac.

Relationship
Boericke

Compare: Uric acid (gout, gouty, eczema, rheumatism, lipoma); Urinum (acne, boils, scurvy, dropsy); Urtica; Tubercul; Thyroid.

Classical Posology

Acute
  • 30C or 200C · repeat every 1–4 h depending on intensity
  • Stop on improvement · reassess in 24–48 h
  • For sensitive / elderly / paediatric: prefer LM1 or 30C
Constitutional
  • 200C or 1M single dose · wait 4 weeks
  • Alternative: LM1 daily × 10 days · ascend on retest
  • Hering's-Law follow-up adapts the next script
Citations: Organon §246 (interval / repetition) · §161 (plussed water) · §282 (LM ascension) · Kent on selection · Vithoulkas on second prescription. Open Repertify for the case-specific dose with the rule cited inline.

Additional notes

UREA PURA
Boericke

Carbamide (UREA)

  • Tuberculosis.
  • Lumps.
  • Enlarged glands.
  • Renal dropsy, with symptoms of general intoxication.
  • Gouty eczema.
  • Albuminuria, diabetes; uraemia.
  • Urine thin and of low specific gravity.
  • A hydrogogue diuretic in the treatment of dropsies.
  • 10 grains every 6 hours.
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