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Materia Medica

Xantoxylum Fraxineum

Prickly Ash
40 sectionsBoericke · 11Clarke · 29

At a glance

Cardinal features · auto-extracted from Boericke · Clarke
  • hemiplegia
  • neuralgic dysmenorrhoea

Essence

Prologue
Boericke

Prickly Ash (XANTHOXYLUM)

  • Its specific action is on the nervous system and mucous membranes.
  • Paralysis, especially hemiplegia.
  • Painful haemorrhages, after-pains, neuralgic dysmenorrhoea, and rheumatic affections, offer a therapeutic field for this remedy, especially in patients of spare habit and nervous, delicate organization.
  • Indigestion from over-eating or from too much fluid.
  • Sluggish capillary circulation.
  • Neurasthenia, poor assimilation, insomnia, occipital headache.
  • Increases mucous secretion of mouth and stimulates the secretion from all glands with ducts opening in the mouth.
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Mentals

Mind
Boericke

Nervous, frightened. Mental depression.

Symptoms — Mind
Clarke

Nervous, frightened feeling.—Easily startled, hysterical—Depression and

weakness.—Indifference and malaise.—Did not care if she lived or died—Seemed entirely void of

ideas.

Generals

Symptoms — Generalities
Clarke

Nerves: acts upon nervous system, mostly upon sensory nerves, but causes a

marked depression of vitality, a non-reactive state; hence its use in chlorosis, measles, neuralgia,

  • &c.
  • , when there is sensorial and bodily depression.
  • —Paralysis of single members.
  • —Hemiplegia
  • (after Nux vom.
  • failed).
  • —Pricking sensation, shocks as from electricity.
  • —Feeling of numbness

through whole I. side of body from head to foot, the division made perceptible in the head,

  • affecting half the nose.
  • -—Whole |.
  • side, esp.
  • |.
  • foot, numb.
  • —Body felt as though it were elastic and

stretched itself out—Seemed as if floor were soft like wool on walking.—As if floating through

air on sitting; as if sunk deep in bed on lying down.—Mucous membrane smarts as from pepper.

Head

Head
Boericke
  • Feels full.
  • Weight and pain on vertex.
  • Pain over eyes, throbbing pressure over nose, pressure in forehead; head seems divided; ringing in ears.
  • Occipital headache.
  • Sick headache with dizziness and flatulence.
Symptoms — Head
Clarke

Giddiness with nausea, < after rising, had to go to bed.—Pain over eyes, with

  • throbbing above root of nose.
  • —Head dull and aching.
  • —Frontal headache.
  • —Intense burning,

pressing, frontal headache, waking her at 4 a.m.; < moving head suddenly; extending into vertex

and orbits; with hot flushes over head and face.—Severe frontal headache; with dizziness.—A dull

headache, in a space not larger than half a dollar, over nose.—Diffused pain in upper part of

  • forehead; < in r.
  • side; pain extends to base of brain, with soreness.
  • —At 6 p.
  • m.
  • sudden and violent

pain over r. eye, with burning through temples; after it, vision blurred.—Throbbing headache

  • over r.
  • eye, with nausea.
  • —Darting pain in |.
  • temple, recurring again and again.
  • —A tightening of

scalp and heavy pain in temples; increase of head difficulties, with a great heat and quiet flowing

(menstrual), being two days in advance of proper time; some headache.—Pain in 1. side of head

  • and |.
  • elbow.
  • —Heavy feeling in top of head.
  • —About upper part of cranium an aching feeling,

accompanied by flashes of throb-like pain, as if top of head were about to be taken off—Pain in

back of head, also a bewildered sensation.—Head feels full——Pressure in head, with fulness of

  • veins.
  • —Tightness of head, with pain increasing over eyes.
  • —L.
  • side of head (and body) numb, the

division made perceptible in head, affecting half the nose.—Headache, with sleepy feeling in

morning.—Shaking head produces a feeling of looseness or quivering of brain, followed by

dizziness.—As if head were surrounded by a tight band (dysmenorrhsa).—Head seemed falling in

pieces.

Eyes

Symptoms — Eyes
Clarke

Watering of eyes and nose.—Eyes bloodshot, with red margins, and feel as if full of

sand.—Lachrymation, pain in lid of r. eye-—Eyes twitched, pupils dilated —Dull, heavy, grinding

pain in |. eye —Ophthalmia.—Vision blurred, as if looking through blue lace-—Atmosphere

appeared blue, and there were flashes of (blue) light before eyes —Objects seem a long way off.

Ears

Symptoms — Ears
Clarke

Ringing in ears, esp. in r—Loud noise in r. ear, as of a valve constantly opening and

  • shutting.
  • —Loud noise like a windmill in 1.
  • ear.
  • —Dull pain in r.
  • ear, seeming to affect jaw socket;

does not know whether his tooth or his ear aches.—Darting pain under and back of r. ear.

Nose

Symptoms — Nose
Clarke

R. nostril seems filled up; discharge of dry and bloody scales of mucus——Numbness

  • throughout I.
  • side of body, division felt in nose.
  • —Dryness of both nostrils.
  • —Discharge of mucus

from nose, with congested feeling, as if it were about to bleed.—Slight nose-bleed —Fluent

coryza.

Face

Face
Boericke

Neuralgia of lower jaw. Dryness of mouth and fauces. Pharyngitis (Wyethia).

Symptoms — Face
Clarke
  • Pain in r.
  • jaw-socket.
  • —Dull pain in |.
  • side of lower jaw.
  • —Hot flushes over face and

head.—Face much flushed.—Pallor even to lips, with heart pains.

Mouth

Symptoms — Mouth
Clarke

Ptyalism; tongue coated yellow.—Peppery taste in mouth, fauces, and

throat —Burning and dry feeling in mouth and tongue.—Tongue seemed to alternately expand and

contract.

Throat

Symptoms — Throat
Clarke

Peppery sensation in throat; soreness, with expectoration of tough mucus.—Feeling

of a bunch in 1. side of throat when swallowing, shifting to r—Throat felt as if in a vice.—Pain

  • and soreness in r.
  • side of throat.
  • —Throbbing in throat and sensation of swelling.
  • —Intense burning

and stinging in Ssophagus, with slight nausea.—Throat dry, very difficult to talk.

Stomach

Symptoms — Appetite
Clarke
  • Very thirsty, drank much at a time.
  • —Unusually hungry.
  • —No appetite.
  • —Anorexia,

could eat but a few mouthfuls at breakfast, and could only drink half a cup of coffee, which was

vomited soon afterward.

Symptoms — Stomach
Clarke

Faintness at stomach as if after fasting; when food was brought cared to eat only

a few mouthfuls, which nauseated her.—Empty eructations, with slight taste of ingesta—Nausea

with headache.—Slight nausea, with sense of oppression at stomach; nausea increased,

accompanied by frequent chills—Feeling of fulness or pressure in epigastrium; fluttering.

Abdomen

Abdomen
Boericke

Griping and diarrhoea. Dysentery, with tympanites, tenesmus; inodorous discharges.

Symptoms — Abdomen
Clarke
  • Some pain in r.
  • side below ribs.
  • —Colic pain in r.
  • iliac region—Rumbling, with

soreness on pressure.—Flatulence.—Griping pain on waking in morning, continued at intervals

through day, with general feeling of indifference and malaise.

Stool

Symptoms — Stool and Anus
Clarke
  • Constipation in morning.
  • —Griping pains 7 a.
  • m.
  • with thin, brown stools,

mixed with mucus.—Burning and pressure for an hour or two after stool.—Epidemic dysentery,

characterised by spasmodic tenesmus, intestinal spasms, tympanitis, &c.—Inodorous discharges

with tenesmus.—Cholera, in stage of collapse.

Urinary

Symptoms — Urinary Organs
Clarke

Urine at night and next morning scanty and high-coloured.—Profuse,

light-coloured urine; nervous women.

Female

Female
Boericke
  • Menses too early and painful.
  • Ovarian neuralgia, with pain in loins and lower abdomen; worse, left side, extending down the thigh, along genito-crural nerves.
  • Neuralgic dysmenorrhoea, with neuralgic headaches; pain in back and down legs.
  • Menses thick, almost black.
  • After-pains (Arnica; Cup; Cham).
  • Leucorrhoea at time of menses.
  • Neurasthenic patients who are thin, emaciated; poor assimilation with insomnia and occipital headache.
Symptoms — Female Sexual Organs
Clarke

Ovarian pain: with scanty and retarded menses; extending down

genito-crural nerves; and sacral pains during pregnancy.—Menses appeared one week before

usual time; attended with a good deal of pain.—Menses eight days before time; flow increased,

bright red; bearing-down pain and pain in r. ovarian region.—Severe constant aching pain in r.

ovarian region, radiating to hip, thighs, and back, with occasional shoots, making her catch her

breath —Sharp, cutting pain in r. ovarian region, extending about hip and down thigh, awoke

  • her.
  • —Cramp-like pain in |.
  • groin, menses five days early.
  • —Pain in |.
  • ovarian region gradually

increasing and gradually decreasing —DysmenorrhSa: with agonising pains, driving patient

almost distracted; neuralgic pain runs along course of genito-crural nerve; in women of spare

habit and of a delicate, nervous temperament; with headache, esp. over |. eye, commencing day

before menses; fulness in head; eyes congested, with photophobia; face flushed and feverish;

agonising bearing down; abundant discharge; excruciating pain in loins and lower

abdomen.—Menstrual flow: too early and profuse; pains down thighs; scanty and

retarded.—Constant headache, < during menses, at which time she also suffered agonising pains

in pelvic region.—Amenorrha for five months; face and legs Sdematous; very nervous, sensitive

to least noise, hysterical mood; voice tremulous; fears she is going to die; general chlorotic

appearance, constipation, scanty, frequent, and dark urine—Amenorrh§a for five months, with

severe pains in r. ovary; constant headache; bearing down and tension in hypogastric

region.—AmenorrhSa from getting feet wet; lasting six months; emaciation with cough; dirty-

grey expectoration; pale face, night-sweats.—Leucorrhsa; profuse, milky-white.—Great increase

of leucorrhsa during the time when menses should appear.—A fter-pains.—Profuse

lochia.—Violent hot pricking in r. ovary (produced immediately by a dose of 3x).

Respiratory

Respiratory
Boericke

Aphonia. Constant desire to take a long breath; oppression of chest. Dry cough, day and night.

Symptoms — Respiratory Organs
Clarke

Hoarseness, with husky feeling in throat; obliged to clear throat

frequently —Aphonia from cold or general debility —Aphonia and pain in lower r. lung on deep

  • inspiration or coughing.
  • —Shortness of breath.
  • —Constant desire to take a long breath.
  • —Cough:

slight hacking cough; in spells, only in open air—Dry cough night and day, from sheer

exhaustion could scarcely turn herself in bed; face pale, bloated; dark rings about eyes; head full

and heavy; lips colourless; tongue pale and flabby; shortness of breath; no appetite; bowels

  • constipated; urine light-coloured, alkaline, sp.
  • gr.
  • 1025; fluttering in stomach, pain in I.
  • side;

limbs weak and bloated.—Had to sit up in bed and turn first one way, then another, as in a severe

fit of asthma, with several spasmodic coughing spells ——Thought she could not get air enough

into lungs, inspiration was so difficult.

Chest

Symptoms — Chest
Clarke

Tightening about chest, with inclination to gape.—Pain in 1. side, under fourth

  • rib.
  • —Sharp pains in r.
  • side of a neuralgic character.
  • —Oppression of chest, with desire to take a

deep inspiration.—Sharp, shooting pains in r. side (like pleurisy pains), occasionally extending

through to shoulder-blade, continual desire to take a long breath —Menses irregular and scanty;

tight, dry cough, which hurts chest and shoulders; bowels almost constantly loose, profuse night-

sweats.

Symptoms — Heart
Clarke

Severe momentary pain in region of heart, making her catch her breath, and turn pale

even to lips; recurred at irregular intervals of from five to thirty minutes; the pain was cutting, <

during inspiration, passed directly through thorax in heart region; immediately after each attack

thirsty, flushed, exhausted.—Pulse irregularly intermittent.—Startled from sleep by severe pain in

heart region, followed by violent action of heart and feeling of suffocation.

Neck & Back

Symptoms — Neck and Back
Clarke

(With headache) pain and stiffness in nape, somewhat > by hard pressure

or throwing head back.—Very severe pain in cervical and upper sacral region.—Back of neck

  • numb.
  • —Slight pain in |.
  • side and under 1.
  • scapula, also in |.
  • hip —Dull pain from nape to r.

scapula.—Dragging pain in lower part of pelvis and back.—Coccyx seemed elongated, extremely

sensitive to pressure and ached all the time; could not sit except on cushion.

Upper Limbs

Symptoms — Upper Limbs
Clarke

Pain in r. shoulder and arm.—Pain and pricking feeling in arm, extending to

  • third finger —Pricking and throbbing sensation in |.
  • arm and fingers.
  • —Severe pain in r.
  • arm,
  • commencing just above bend of elbow.
  • —Whole |.
  • arm and shoulder numb.
  • —Pain in |.
  • elbow and
  • 1.
  • side of head.
  • —Dull pain in |.
  • elbow, passing to palm of hand, then to shoulder.
  • —Pain in both
  • elbows.
  • —Severe pain in wrist, extending to thumb.
  • —A flash of pain in r.
  • thumb, extending to

hand.

Lower Limbs

Symptoms — Lower Limbs
Clarke

Severe neuralgic pains in course of genito-crural nerves

  • (dysmenorrhsa).
  • —Excessive weakness of lower limbs (chlorosis).
  • —Pain in 1.
  • leg, between hip and

knee.—Weakness in lower limbs, with pain in knees; pain of extremities increased, accompanied

  • by frequent chills.
  • —Legs and feet feel tired.
  • —Pain in I.
  • knee very severe; pain has lasted, without
  • cessation, a little more than half an hour.
  • —Dull pain in r.
  • knee.
  • —A flash of pain in calf of r.
  • leg.
  • —Pain in ankle.
  • —Pain in |.
  • heel.
  • —Pain in both feet, shooting up to knees.
  • —L.
  • foot numb.

Extremities

Extremities
Boericke
  • Paralysis of left side following spinal disorders.
  • Numbness of left side; impairment of nerves of motion.
  • Hemiplegia.
  • Pain in nape, extending down back.
  • Sciatica; worse, hot weather.
  • Anterior, crural neuralgia (Staph).
  • Left arm numb.
  • Neuralgic shooting pain, as from electricity, all over limb.

Skin

Symptoms — Skin
Clarke

Measles, dulness, bewilderment, drowsiness, want of sufficient development of the

eruption.—Old and indolent ulcers.

Sleep

Sleep
Boericke

Hard and unrefreshing; dreams of flying. Sleeplessness in neurasthenics.

Symptoms — Sleep
Clarke

Continued gaping; drowsiness.—Slept hard and heavy; dreamed of flying about over

tops of houses.—A dream of suffocation woke her.—Dreamed the throat grew up, and woke with

fright, finding it difficult to breathe —Awoke in morning languid and depressed.

Fever

Symptoms — Fever
Clarke

Sense of heat all over veins, with a desire to be bled; flash of heat from head to

foot—Slight chill accompanied by death-like nausea.—Frequent chills, with pains in extremities;

nausea.—Typhoid fever in stage of collapse.

Clinical

Clinical (part 1)
Clarke
  • A fter-pains.
  • Asthma.
  • Coccygodynia.
  • DysmenorrhSa.
  • Earache.
  • Fibroma.
  • Headache.
  • Hemiplegia.
  • Hysteria.
  • Jaw-joint, pain in.
  • Levitation.
  • Menstruation, painful.
  • Nerves, injured.
  • Nervousness.
  • Neuralgia; crural.
  • Ophthalmia.
  • Sciatica.
  • Toothache.
  • Ulcers.
Clinical (part 2)
Clarke

Characteristics—According to Hale, Rafinesque was the first to investigate Xanthoxylum,

which was known to him as "a great article in the materia medica of our Indians"; who use the

root bark in decoction for "colics, gonorrhSa, syphilis, inward pains, toothache, ulcers, &c. It is a

great topical stimulant," he continues, "changing the nature of malignant ulcers." Xan. contains

  • Piperin.
  • T.
  • C.
  • Duncan (Minn.
  • H.
  • M.
  • , ix.
  • 340), recounting reminiscences of his boyhood, says:

"There was another drug that set my youthful mouth and stomach on fire, and that was Prickly

Ash. You wanted to open the mouth to let the cool air get in." This warmth is felt as a warm

glow through the entire system, with a sensation in the nerves as if gentle shocks of electricity

were passing through the body. In one of Cullis' provers, Miss D. (there were six provers, three

of them women; all took the © tincture), the entire left half of the body became numb, the left

half of the head being sharply divided in sensation from the other half. These symptoms, with the

many head pains and fulness in the head, give the correspondence in hemiplegia, in which Xan.

  • has been given with success.
  • Two additional provings on women appear in C.
  • D.
  • P.
  • (quoting
  • from Publ.
  • Mass.
  • Hom.
  • Soc.
  • ).
  • In these provings 20- to 100-drop doses of the tincture were taken,

and symptoms of great severity were produced. Both provers had severe dysmenorrhsal pains,

with increased and anticipating flow. This is the characteristic of Xan. The symptoms in each

case roused the prover from sleep with pain and suffocation; the pain being confined to head,

heart, throat, and pelvis. Many of the pains were radiating—from above right eye over head; from

right ovary down thigh and in other directions. Left-sided numbness was present in one; who

also had symptoms of levitation and disordered sensation. In dysmenorrhsa Xan. has a wide

range. Cullis, who had most success in cases of dysmenorrhsa and amenorrhsa, relates these

cases: (/) Miss A., 25, brunette, had menstrual irregularity since commencement; would go

three, four, or five months, and then her sufferings were excruciating. When she came under

  • treatment had had no menses for two months.
  • Xan.
  • 1 was given, 5 drops thrice daily.
  • Menses

appeared in three days and were painless. (2) Miss B., fair, nervous, had menses suppressed by

getting feet wet, being then a week over time. Xan. 1x, 5 drops every three hours, brought on

menses next day. Cullis thinks Xan. especially Suited to women of spare habit, nervous

temperament, and delicate organisations. Leucorrhsa with amenorrhSa he regards as a strong

  • indication.
  • P.
  • C.
  • Majumdar (/nd.
  • H, R.
  • , viti.
  • 21) cured a case of uterine fibroid with Xan.
  • 3x: An

emaciated, feeble, wrinkled woman, 56, widow, had been advised by allopaths to have an

operation for tumour. Menstruation had ceased fifteen years before. It had always been profuse

and painful, and preceded and followed by leucorrhsa. She had neuralgic pain in right ovarian

region; a hard nodular tumour size of a small orange, painful on deep pressure. Fetid, yellowish

white discharge from vagina. Patient was nervous, depressed; lazy and sleepy even in the

  • daytime.
  • Appetite poor; disgust for food.
  • Xan.
  • 3x was given night and morning.
  • In a week the

pain was better and discharge less. In four weeks Majumdar found the patient a changed person.

The tumour was much softer and reduced by half. In six months the tumour had gone, and the

Clinical (part 3)
Clarke
  • patient was quite well, Xan.
  • having been taken intermittently all the time.
  • Xan.
  • belongs to the

Rutacec, and, like Ruta, has a vulnerary action, as I discovered in this case: Miss X., 28, injured

her right ulnar nerve at the elbow by repeatedly striking it against the edge of a bath whilst

washing some articles. For two months she had had to keep the arm in a sling. A few weeks after

that the arm swelled. Some eight months after the injury I saw her. The pain centred in the ulnar

nerve where it crosses the inner condyle of the humerus, though there was pain above and below

as well. I gave Ruta 30, which gave some relief to the pain, and relieved a frontal headache to

  • which the patient was subject.
  • The arm becoming less well, I gave Xan.
  • 12 four times a day.
  • This

made a distinct improvement in the arm, and also relieved a dysmenorrhSa to which Miss X. was

subject. After persistent treatment with various attenuations of Xan. the nerve lost its

sensitiveness, and the patient could use her arm freely. Xan. 1 in five-drop doses night and

  • morning, with a liniment of Xan.
  • © , proved most effective.
  • A patient to whom I gave Xan.
  • 3x

had immediately a hot pricking pain in right ovary. Among the Peculiar Sensations are: As if top

of head would be taken off by flashes of throb-like pain. As if bewildered with pain in back of

  • head.
  • Feeling of looseness or quivering of brain.
  • As if head falling to pieces.
  • As if head
  • surrounded by a tight band.
  • Eyes as if full of sand.
  • As if pepper in mouth and throat.
  • As of a

bunch in throat. Tongue as if expanding and contracting. As if throat swollen and enlarged.

  • Throat as if in a vice.
  • Back of neck as if stiff.
  • Coccyx as if elongated.
  • As if floating in the air.
  • As
  • if walking on wool.
  • As if sunk deep in bed.
  • As if body expanded.
  • Many pains are radiating; some

are sudden, arouse from sleep, and cause the patient to catch her breath. Pains are excruciating,

unbearable, and are accompanied with red, hot face; but the heart pains = pallor. The symptoms

are: < By moving head suddenly. Neck pain is > by pressure and by throwing head back. Lying

  • down >.
  • Drink of ice-water >.
  • Headache is > by cold water and in open air.
  • Pains are < in

morning; 4 a.m.

Relations

Relations
Clarke

Compare: Head, heart, and uterus, Act. r. Lack of eruption in measles, Bry.

Dysmenorrhsa with reflex neuralgia, Coloc. DysmenorrhSa and sciatica: numbness, Gnaphal.

  • Dysmenorrh§a, Vib.
  • 0.
  • , Caulo.
  • After-pains, Pul.
  • , Cham.
  • , Cup.
  • Pains increase and decrease
  • gradually, Stan.
  • Levitation, Can.
  • i.
  • , Stic.
  • p.
  • , Ph.
  • ac.
  • Headache over root of nose, Ign.
  • Headache

over right eye, Sang. Heart and uterus, Cact.

Relationship
Boericke
  • Compare: Gnaph; Cimicif; Staph; Mezer; Piscidia-White dogwood--(a nerve sedative.
  • Insomnia due to worry, nervous excitement, spasmodic coughs; pains of irregular menstruation; regulates the flow.
  • Neuralgic and spasmodic affections.
  • Use tincture in rather material doses).

Posology

Dose
Boericke

First to sixth potency.

Classical Posology

Acute
  • 30C or 200C · repeat every 1–4 h depending on intensity
  • Stop on improvement · reassess in 24–48 h
  • For sensitive / elderly / paediatric: prefer LM1 or 30C
Constitutional
  • 200C or 1M single dose · wait 4 weeks
  • Alternative: LM1 daily × 10 days · ascend on retest
  • Hering's-Law follow-up adapts the next script
Citations: Organon §246 (interval / repetition) · §161 (plussed water) · §282 (LM ascension) · Kent on selection · Vithoulkas on second prescription. Open Repertify for the case-specific dose with the rule cited inline.

Additional notes

Symptoms — Limbs
Clarke

Suddenly taken with cramp-like pains in wrists and knees.—Pain in limbs, neuralgic,

  • shooting; numbness and weakness.
  • —Dull pain in |.
  • knee; also in 1.
  • elbow, extending to hand, then

in |. side and top of 1. foot.

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