Thiosinaminum

Thios. belongs to the same chemical group as Urea. The colourless bitter

crystals are soluble in water, alcohol, and ether. Thios. has been used externally and internally in

cases of lupus, chronic glandular tumours, and for dissolving scar tissue; and internally for

resolving tumours of the uterine appendages. The usual internal dose in old-school practice is 4

• ▸to 8 grains once a day given hypodermically in a 15 per cent.
• ▸solution.
• ▸C.
• ▸H.
• ▸Pennoyer (quoted

• ▸Pac.
• ▸C.
• ▸J.
• ▸of H.
• ▸viii.
• ▸199) relates this case: Mrs.
• ▸C.
• ▸, 69, had been several years ill with gastric

distress, sciatica, pains in hips down to knees; < by motion. Indigestion, flatulence of stomach

and bowels, < after eating. Pain in back. Inability to walk; much perspiration; depression of

spirits; and subnormal temperature. Her father had died at 69 of stomach trouble; mother at 58 of

stricture of the bowel. Examination showed stricture of rectum two inches above anus, there

being a tense fibrous band forming a ring opening, which would not admit the index finger.

Bougies and mechanical measures failed to relieve. Weakness was so great, patient would faint

at stool. Under general treatment nutrition improved, but the local condition was unchanged. A

• ▸year later the stricture was slightly increased.
• ▸Thios.
• ▸was now given, gr.
• ▸ii.
• ▸twice daily.
• ▸The

following year the patient was found much improved. Examination showed that the cicatricial

band had gone, the speculum could be introduced, and the mucous membrane was normal in

• ▸appearance, though not as distensible as a normal rectum should be.
• ▸W.
• ▸Spencer (H.
• ▸M.
• ▸, xxxiv.

55) has applied this property of resolving cicatricial tissues in cases of tinnitus auri'um "where the

ossicles are bound down, and the function of the tympanic cavity so much impaired by fibrous

bands or adhesions." In such cases he has had encouraging success. Enlarged lymphatic glands

have been reduced in the same way. A few symptoms observed on patients under treatment I

have arranged in the Schema with some cured symptoms.

Sensation of heat and burning in affected parts—Bodily weight

increased.—Glandular swellings reduced.

Distinct local reaction in lupus cases after a few hours.—Urticaria—Lupus.—Scar

tissues.

• ▸Adhesions.
• ▸Cicatrices.
• ▸Lupus.
• ▸Lymphatic glands, enlarged.
• ▸Rectum, stricture of.

Strictures. Tinnitus aurium. Tumours.

• ▸Compare: Botan.
• ▸, Sinapis and Crucifer¢.
• ▸Uterine tumours, Thlasp.
• ▸b.
• ▸p.
• ▸Diuresis

• ▸(also chemical) Urea.
• ▸Lupus, Tub.
• ▸Cicatrices.
• ▸Sil.
• ▸, Fl.
• ▸ac.
• ▸Affections of rectum, Nit.
• ▸ac.
• ▸, Graph.
• ▸,

Scirrh.

• ▸Inject under skin, or, into the lesion a 10 per cent solution in glycerine and water, 15-30 drops twice a week.
• ▸Internally in capsules 1/2 grain daily.
• ▸Obstinate arterio-sclerotic ailments in doses of 1/2 grain, never more, 3 times a day.
• ▸Vertigo and arthritis (Bartlett).
• ▸2x attenuation.

• ▸Arterio-sclerotic vertigo. Tinnitus.
• ▸Catarrhal deafness with cicatricial thickening.
• ▸Subacute suppurative otitis media, formation of fibrous bands impeding free movement of the ossicles.
• ▸Thickened drum.
• ▸Deafness due to some fibrous change in the nerve.